Recombinant Human Cell Adhesion Molecule 2, His-tagged

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Recombinant Human Cell Adhesion Molecule 2, His-tagged

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Cat. No. : CADM2-5605H
Product Overview : Recombinant Human CADM2protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag.Ala21-Asp335.
Description : CADM2 is animmunoglobulin super family member that is also designated as synaptic celladhesion molecule 2 and nectin-like protein 3. The four CADM2 proteins,designated A, B, C and D, are type I transmembrane glycoproteins expressedmainly in epithelial cells that contain one V-type Ig-like and two C2-typeIg-like domains in their extracellular regions. These domains arecharacteristically responsible for Ca2+ independent homophilic andheterophilic interactions in the brain, lung, kidney, bladder, prostate andtestis.
Source : Mammalian cells
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminalSequence : Ala21
Molecular Weight : 35.5 kDa
Activity : Measuredby its ability to enhance neurite outgrowth of E16-E18 rat embryonic corticalneurons. Able to significantly enhance neurite outgrowth when immobilized asa 3 μL droplet containing 50 ng on a nitrocellulose-coated microplate.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE : 36-55kDa, reducing conditions
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstituteat 100 μg/mL in sterile PBS
Storage : Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : CADM2 cell adhesion molecule 2[ Homo sapiens ]
Official Symbol : CADM2
Synonyms : CADM2; cell adhesionmolecule 2; NECL3; IGSF4D; Necl-3; synCAM2; nectin-like 3; nectin-likeprotein 3; immunoglobulin superfamily member 4D; immunoglobulin superfamily,member 4D; MGC104534; MGC138341; MGC138343; OTTHUMP00000213814;OTTHUMP00000213815; OTTHUMP00000213816; SYNCAM2
Gene ID : 253559
mRNA Refseq : NM_001167674
Protein Refseq : NP_001161146
MIM : 609938
UniProt ID : Q8N3J6
Chromosome Location : 3p12.2
Pathway : Adherens junctionsinteractions; Cell junction organization; Cell-Cell communication; Cell-celljunction organization
Function : adherens junctionorganization; cell junction assembly; cell-cell junction organization
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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