Active Recombinant Mouse Chemokine (C-X3-C motif) Ligand 1

• Cat.No.: Cx3cl1-379M
• Product Overview: Recombinant mouse Cx3cl1protein was expressed in E. coli. Leu22-Lys105.

Specification

• Cat. No.: Cx3cl1-379M
• Description: Cx3cl1 is a largecytokine protein of 373 amino acids; it contains multiple domains and is theonly known member of the CX3C chemokine family. It is alsocommonly known under the names fractalkine (in humans) and neurotactin (inmice). The polypeptide structure of Cx3cl1 differs from thetypical structure of other chemokines.
• Source: E. coli
• Form: Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
• N-terminal Sequence: Leu22
• Molecular Weight: 9.5 kDa
• Activity: Measured by itsability to chemoattract mouse CX3CR1 transfected BaF3 mouse pro-B cells. TheED50 for this effect is typically 10-50 ng/mL.
• Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
• Purity: >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
• Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.

Gene Information

• Gene Name: Cx3cl1 chemokine (C-X3-C motif)ligand 1 [ Mus musculus ]
• Official Symbol: Cx3cl1
• Synonyms: Cx3cl1; chemokine (C-X3-Cmotif) ligand 1; CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747;D8Bwg0439e; fractalkine; neurotactin; C-X3-C motif chemokine 1; small-induciblecytokine D1; CX3C membrane-anchored chemokine; small inducible cytokinesubfamily D, 1; Fkn; Cx3C
• Gene ID: 20312
• mRNA Refseq: NM_009142
• Protein Refseq: NP_033168
• UniProt ID: O35188
• Chromosome Location: 8
• Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodesian-likereceptors); Cytokine-cytokine receptor interaction; GPCR ligand binding;Peptide ligand-binding receptors; Signal Transduction; Signaling by GPCR
• Function: chemokine activity; cytokineactivity