"Ppbp" Related Products


Recombinant Mouse Pro-Platelet Basic Protein

Cat. No. : Ppbp-394M
Product Overview : Recombinantmouse Ppbp protein was expressed in E. coli. Lys40-Tyr113.
Description : Ppbp is a proteinthat is released in large amounts from platelets following their activation.It stimulates various processes including mitogenesis, synthesis ofextracellular matrix, glucose metabolism and synthesis of plasminogenactivator.
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein.
N-terminal Sequence : Lys40
Molecular Weight : 8.2 kDa
Activity : Measured by itsability to chemoattract human CXCR2 transfected BaF3 mouse pro-B cells. TheED50 for this effect is typically 0.2-1 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 25μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
PDBrendering based on 1f9p. :

Gene Name : Ppbppro-platelet basic protein [ Mus musculus ]
Official Symbol : Ppbp
Synonyms : Ppbp; pro-plateletbasic protein; TGB; LDGF; MDGF; TGB1; CTAP3; Cxcl7; NAP-2; Scyb7;b-TG1; LA-PF4; THBGB1; CTAPIII; beta-TG; AI854500; NAP-2-L1; 2400003M24Rik; plateletbasic protein; chemokine (C-X-C) ligand 7; chemokine (C-X-C) ligand 7,isoform CRA_b; chemokine subfamily B Cys-X-Cys; Thymus chemokine 1;Uncharacterized protein; mCG_1702
Gene ID : 57349
mRNA Refseq : NM_023785
Protein Refseq : NP_076274
UniProt ID : Q9EQI5
Chromosome Location : 5
Pathway : Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; G alpha (i) signallingevents; GPCR downstream signaling; GPCR ligand binding; Hemostasis; Peptideligand-binding receptors; Platelet activation, signaling and aggregation; Plateletdegranulation; Response to elevated platelet cytosolic Ca2+; SignalTransduction; Signaling by GPCR
Function : Molecular function

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