"Ppbp" Related Products

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Recombinant Mouse Pro-Platelet Basic Protein

Cat. No.: Ppbp-394M
Product Overview: Recombinantmouse Ppbp protein was expressed in E. coli. Lys40-Tyr113.
Description: Ppbp is a proteinthat is released in large amounts from platelets following their activation.It stimulates various processes including mitogenesis, synthesis ofextracellular matrix, glucose metabolism and synthesis of plasminogenactivator.
Source: E. coli
Form: Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein.
N-terminal Sequence: Lys40
Molecular Weight: 8.2 kDa
Activity: Measured by itsability to chemoattract human CXCR2 transfected BaF3 mouse pro-B cells. TheED50 for this effect is typically 0.2-1 ng/mL.
Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
Purity: >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstitute at 25μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
Gene Name: Ppbppro-platelet basic protein [ Mus musculus ]
Official Symbol: Ppbp
Synonyms: Ppbp; pro-plateletbasic protein; TGB; LDGF; MDGF; TGB1; CTAP3; Cxcl7; NAP-2; Scyb7;b-TG1; LA-PF4; THBGB1; CTAPIII; beta-TG; AI854500; NAP-2-L1; 2400003M24Rik; plateletbasic protein; chemokine (C-X-C) ligand 7; chemokine (C-X-C) ligand 7,isoform CRA_b; chemokine subfamily B Cys-X-Cys; Thymus chemokine 1;Uncharacterized protein; mCG_1702
Gene ID: 57349
mRNA Refseq: NM_023785
Protein Refseq: NP_076274
UniProt ID: Q9EQI5
Chromosome Location: 5
Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; G alpha (i) signallingevents; GPCR downstream signaling; GPCR ligand binding; Hemostasis; Peptideligand-binding receptors; Platelet activation, signaling and aggregation; Plateletdegranulation; Response to elevated platelet cytosolic Ca2+; SignalTransduction; Signaling by GPCR
Function: Molecular function

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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