"Amica1" Related Products


Recombinant Mouse Adhesion Molecule, Interacts With CXADR Antigen 1

Cat. No. : Amica1-447M
Product Overview : Recombinant Mouse Amica1protein was expressed in Murine myeloma cell line. Leu23-Leu281.
Description : Amica1 is a 65kDa, type I transmembrane glycoprotein that belongs to the junctionaladhesion molecule (JAM) subset of the immunoglobulin superfamily. JAM familyproteins contribute to intercellular connections within epithelial andendothelial cell layers and mediate their interactions with varioushemopoietic cells. The mouse Amica1 cDNA encodes a 379amino acid (aa) precursor that includes a 20 aa signal sequence, a 261 aaextracellular domain (ECD) with two Iglike domains, a 21 aa transmembranesegment, and a 77 aa cytoplasmic domain. In contrast to other JAM familyproteins, AMICA does not contain a cytoplasmic PDZ binding motif.
Source : Murine myeloma cellline, NS0-derived.
Form : Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence : Leu23
MolecularWeight : 56.6 kDa (monomer)
Activity : Measuredby the ability of the immobilized protein to support the adhesion of human neutrophils.When 2 x 105 cells/well are added to rmAMICAcoated plates (10 μg/mL, 100μL/well), 30 50% of the cells will adhere after 20 minutes at 37°C.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
Purity : >95%,by SDSPAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin sterile PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, 20 to 70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, 20 to 70°C under sterile conditions after reconstitution.
Gene Name : Amica1 adhesion molecule,interacts with CXADR antigen 1 [ Mus musculus ]
Official Symbol : Amica1
Synonyms : Amica1; adhesionmolecule, interacts with CXADR antigen 1; AMICA; Crea7; Gm638;junctional adhesion molecule-like; mCrea7; adhesion molecule AMICA; dendriticcell-specific protein CREA7; dendritic-cell specific protein Crea7
Gene ID : 270152
mRNA Refseq : NM_001005421
Protein Refseq : NP_001005421
UniProt ID : Q80UL9
Chromosome Location : 9
Function : cell adhesionmolecule binding

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