"FUCA1" Related Products


Recombinant Human Fucosidase, Alpha-L- 1, Tissue, His-tagged

Cat. No.: FUCA1-471H
Product Overview: Recombinant Human FUCA1protein was expressed in Murine myeloma cell line with an N-terminal CD33 signalsequence and a C-terminal 6-His tag. Gln32-Lys466.
Description: Fucosylated glycoconjugatesplay numerous roles in biological processes, such as development, apoptosis andthe immune responses, and are involved in the pathology of inflammation, cancerand cystic fibrosis. Tissue α LFucosidase, also known as FUCA1, is a lysosomalenzyme responsible for hydrolyzing αLfucose moieties from glycolipids and oligosaccharides.
Source: Murine myeloma cell line,NS0-derived
Form: Supplied as a 0.2 μmfiltered solution in Tris and NaCl.
N-terminalSequence: Gln32
Molecular Weight: 51 kDa
Activity: Measuredby its ability to cleave a fluorogenic substrate 4-methylumbelliferyl-α-L-fucopyranoside.The specific activity is > 4800 pmol/min/μg, as measured under the describedconditions. See Activity Assay Protocol.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Bluestain at 5 μg per lane.
Storage: Use a manualdefrost freezer and avoid repeated freezethaw cycles. 6 months from date of receipt,20 to 70 °C as supplied. 3 months, 20 to 70°C under sterile conditions after opening.
Gene Name: FUCA1 fucosidase, alpha-L- 1, tissue[ Homo sapiens ]
Official Symbol: FUCA1
Synonyms: FUCA1; fucosidase,alpha-L- 1, tissue; FUCA; tissue alpha-L-fucosidase; alpha-L-fucosidase 1; alpha-L-fucosidaseI; alpha-L-fucoside fucohydrolase 1; EC; Nbla10230
Gene ID: 2517
mRNA Refseq: NM_000147
Protein Refseq: NP_000138
MIM: 612280
UniProt ID: P04066
Chromosome Location: 1p34
Pathway: Lysosome; Other glycandegradation
Function: alpha-L-fucosidase activity;cation binding; hydrolase activity; sugar bindin

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