Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Arsenic (+3 oxidation state) Methyltransferase, His-tagged

Cat.No. : AS3MT-6784H
Product Overview : Recombinant humanAS3MT protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques
  • Specification
  • Gene Information
  • Related Products
Cat. No. : AS3MT-6784H
Description : AS3MT catalyzes thetransfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalentarsenical and may play a role in arsenic metabolism
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl
Molecular Weight : 44.3kDa(399aa),confirmed by MALDI-TOF
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMAALRD AEIQKDVQTY YGQVLKRSAD LQTNGCVTTA RPVPKHIREA LQNVHEEVALRYYGCGLVIP EHLENCWILD LGSGSGRDCY VLSQLVGEKG HVTGIDMTKG QVEVAEKYLD YHMEKYGFQASNVTFIHGYI EKLGEAGIKN ESHDIVVSNC VINLVPDKQQ VLQEAYRVLK HGGELYFSDV YTSLELPEEIRTHKVLWGEC LGGALYWKEL AVLAQKIGFC PPRLVTANLI TIQNKELERV IGDCRFVSAT FRLFKHSKTGPTKRCQVIYN GGITGHEKEL MFDANFTFKE GEIVEVDEET AAILKNSRFA QDFLIRPIGE KLPTSGGCSALELKDIITDP FKLAEESDSM KSRCVPDAAG GCCGTKKSC
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : AS3MTarsenic (+3 oxidation state) methyltransferase [ Homo sapiens ]
Official Symbol : AS3MT
Synonyms : AS3MT; arsenic (+3 oxidation state)methyltransferase; arsenite methyltransferase; CYT19; 2310045H08Rik; Arsenic(+3 oxidation state) methyltransferase; Arsenite methyltransferase; AS3MT;C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonitemethyltransferase; Methyltransferase cyt19; OTTHUMP00000020384;RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase;OTTHUMP00000020384; methyltransferase cyt19; methylarsonitemethyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase;S-adenosyl-L-methionine:arsenic(III) methyltransferase; RP11-753C18.6
Gene ID : 57412
mRNA Refseq : NM_020682
Protein Refseq : NP_065733
MIM : 611806
Uniprot ID : Q9HBK9
Chromosome Location : 10q24.33
Pathway : arsenate detoxification I,conserved biosystem
Function : arsenite methyltransferaseactivity; methylarsonite methyltransferase activity; methyltransferaseactivity; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
Why is the AS3MT protein important? 10/26/2021

The AS3MT protein plays a crucial role in the detoxification and elimination of arsenic from the body, preventing its accumulation and potential toxicity.

How does the AS3MT protein interact with arsenic? 08/26/2021

The AS3MT protein binds to and methylates inorganic arsenic, facilitating its conversion into organic arsenic metabolites that are easier to eliminate from the body.

Is the AS3MT protein involved in the metabolism of other substances? 07/23/2021

The AS3MT protein is primarily associated with the metabolism of arsenic and has not been extensively linked to the metabolism of other substances.

What happens when the AS3MT protein is impaired or dysfunctional? 08/02/2018

Impairment or dysfunction of the AS3MT protein can lead to reduced arsenic methylation ability, potentially increasing arsenic toxicity in the body.

Can alterations in AS3MT gene expression affect arsenic methylation? 09/20/2017

Yes, alterations in AS3MT gene expression can influence the methylation capacity of arsenic, potentially leading to variations in arsenic toxicity levels.

Are there any genetic variations in the AS3MT gene? 06/24/2017

Yes, genetic variations in the AS3MT gene have been identified and can influence the activity and expression of the AS3MT protein.

Is the AS3MT protein associated with any diseases or conditions? 01/28/2016

The AS3MT protein is associated with arsenic-induced diseases and conditions, such as arsenic poisoning, arsenic-related cancers, and cardiovascular diseases.

Customer Reviews (3)

Write a review
Reviews
09/13/2019

    The AS3MT Protein has exceeded my expectations by consistently delivering outstanding results and providing exceptional technical support.

    01/27/2019

      In addition to its remarkable quality and exceptional technical support, the AS3MT Protein boasts an impressive range of applications.

      06/05/2018

        Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

        Ask a Question for All AS3MT Products

        Required fields are marked with *

        My Review for All AS3MT Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends