Recombinant Human Arsenic (+3 oxidation state) Methyltransferase, His-tagged
Cat.No. : | AS3MT-6784H |
Product Overview : | Recombinant humanAS3MT protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques |
- Specification
- Gene Information
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Cat. No. : | AS3MT-6784H |
Description : | AS3MT catalyzes thetransfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalentarsenical and may play a role in arsenic metabolism |
Form : | Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl |
Molecular Weight : | 44.3kDa(399aa),confirmed by MALDI-TOF |
Purity : | > 90% by SDS -PAGE |
Concentration : | 1 mg/ml (determinedby Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMAALRD AEIQKDVQTY YGQVLKRSAD LQTNGCVTTA RPVPKHIREA LQNVHEEVALRYYGCGLVIP EHLENCWILD LGSGSGRDCY VLSQLVGEKG HVTGIDMTKG QVEVAEKYLD YHMEKYGFQASNVTFIHGYI EKLGEAGIKN ESHDIVVSNC VINLVPDKQQ VLQEAYRVLK HGGELYFSDV YTSLELPEEIRTHKVLWGEC LGGALYWKEL AVLAQKIGFC PPRLVTANLI TIQNKELERV IGDCRFVSAT FRLFKHSKTGPTKRCQVIYN GGITGHEKEL MFDANFTFKE GEIVEVDEET AAILKNSRFA QDFLIRPIGE KLPTSGGCSALELKDIITDP FKLAEESDSM KSRCVPDAAG GCCGTKKSC |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | AS3MTarsenic (+3 oxidation state) methyltransferase [ Homo sapiens ] |
Official Symbol : | AS3MT |
Synonyms : | AS3MT; arsenic (+3 oxidation state)methyltransferase; arsenite methyltransferase; CYT19; 2310045H08Rik; Arsenic(+3 oxidation state) methyltransferase; Arsenite methyltransferase; AS3MT;C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonitemethyltransferase; Methyltransferase cyt19; OTTHUMP00000020384;RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase;OTTHUMP00000020384; methyltransferase cyt19; methylarsonitemethyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase;S-adenosyl-L-methionine:arsenic(III) methyltransferase; RP11-753C18.6 |
Gene ID : | 57412 |
mRNA Refseq : | NM_020682 |
Protein Refseq : | NP_065733 |
MIM : | 611806 |
Uniprot ID : | Q9HBK9 |
Chromosome Location : | 10q24.33 |
Pathway : | arsenate detoxification I,conserved biosystem |
Function : | arsenite methyltransferaseactivity; methylarsonite methyltransferase activity; methyltransferaseactivity; transferase activity |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (7)
Ask a questionThe AS3MT protein plays a crucial role in the detoxification and elimination of arsenic from the body, preventing its accumulation and potential toxicity.
The AS3MT protein binds to and methylates inorganic arsenic, facilitating its conversion into organic arsenic metabolites that are easier to eliminate from the body.
The AS3MT protein is primarily associated with the metabolism of arsenic and has not been extensively linked to the metabolism of other substances.
Impairment or dysfunction of the AS3MT protein can lead to reduced arsenic methylation ability, potentially increasing arsenic toxicity in the body.
Yes, alterations in AS3MT gene expression can influence the methylation capacity of arsenic, potentially leading to variations in arsenic toxicity levels.
Yes, genetic variations in the AS3MT gene have been identified and can influence the activity and expression of the AS3MT protein.
The AS3MT protein is associated with arsenic-induced diseases and conditions, such as arsenic poisoning, arsenic-related cancers, and cardiovascular diseases.
Customer Reviews (3)
Write a reviewThe AS3MT Protein has exceeded my expectations by consistently delivering outstanding results and providing exceptional technical support.
In addition to its remarkable quality and exceptional technical support, the AS3MT Protein boasts an impressive range of applications.
Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
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