|Cat. No. :
|Product Overview :
||Recombinanthuman STX3 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.
||STX3 belongs tothe syntaxin family. syntaxin family is cellular receptors for transportvesicles which participate in exocytosis in neutrophils.STX3 has an important role in the growth of neurites and serves as a directtarget for omega-6 arachidonic acid.
||Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 100mM NaCl.
|Molecular Weight :
||33.2kDa (288aa),confirmed by MALDI-TOF
||> 95% by SDS-PAGE
||1 mg/ml(determined by Bradford assay)
|Sequences of aminoacids :
||MGSSHHHHHHSSGLVPRGSH MGSHMMKDRL EQLKAKQLTQ DDDTDAVEIA IDNTAFMDEFFSEIEETRLN IDKISEHVEE AKKLYSIILS APIPEPKTKD DLEQLTTEIK KRANNVRNKL KSMEKHIEEDEVRSSADLRI RKSQHSVLSR KFVEVMTKYN EAQVDFRERS KGRIQRQLEI TGKKTTDEEL EEMLESGNPAIFTSGIIDSQ ISKQALSEIE GRHKDIVRLE SSIKELHDMF MDIAMLVENQ GEMLDNIELN VMHTVDHVEKARDETKKAVK YQSQARKK
||Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
|Pathway||Botulinum neurotoxicity; Neuronal System; Proteolyticcleavage of SNARE complex proteins; Proteolytic cleavage of SNARE complexproteins; Synaptic vesicle cycle|