Recombinant Human Aldehyde Dehydrogenase 6 Family, Member A1, GST-tagged ALDH6A1-501H

Recombinant Human Aldehyde Dehydrogenase 6 Family, Member A1, GST-tagged

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Recombinant Human Aldehyde Dehydrogenase 6 Family, Member A1, GST-tagged

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Cat. No. : ALDH6A1-501H
Product Overview : Recombinant Human ALDH6A1protein was expressed as gst-tagged fusion protein by E. coli and purified byGSH-sepharose. The purified protein was resolved in 1M PBS (58mM Na2HPO4, 17mMNaH2PO4, 68mM NaCl, pH8.) added with 100mM GSH and 1% TritonX-100,15%glycerol.
Description : ALDH6A1 belongs tothe aldehyde dehydrogenases family of proteins. ALDH6A1 plays a role in the valineand pyrimidine catabolic pathways. Methylmalonate semialdehyde dehydrogenasedeficiency is characterized by elevated beta-alanine, 3-hydroxypropionicacid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urineorganic acids.
Host : E. coli
Antigen peptideregion : C-342aa
Full length : False
Storage : Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.
Gene Name : ALDH6A1 aldehyde dehydrogenase 6family, member A1 [ Homo sapiens ]
Official Symbol : ALDH6A1
Synonyms : ALDH6A1;aldehyde dehydrogenase 6 family, member A1; MMSDH; MMSADHA; MGC40271;methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial;malonate-semialdehyde dehydrogenase; aldehyde dehydrogenase family 6 memberA1; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; EC1.2.1.18; EC 1.2.1.27
Gene ID : 4329
mRNA Refseq : NM_005589
Protein Refseq : NP_005580
MIM : 603178
UniProt ID : Q02252
Chromosome Location : 14q24.3
Pathway : Branched-chain aminoacid catabolism; Inositol phosphate metabolism; Malonate semialdehydepathway; Metabolic pathways; Metabolism; Metabolism of amino acids andderivatives; Propanoate metabolism; Valine; beta-Alanine metabolism;beta-alanine degradation I; valine degradation I
Function : fatty-acyl-CoAbinding; malonate-semialdehyde dehydrogenase (acetylating) activity;methylmalonate-semialdehyde dehydrogenase (acylating) activity;oxidoreductase activity

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