Recombinant Human SNIP1, His-tagged
Cat.No. : | SNIP1-3537H |
Product Overview : | Recombinant humanSNIP1 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SNIP1-3537H |
Description : | SNIP1is smad nuclear interacting protein contains a forkhead-associated (FHA)domain and acts as a nuclear inhibitor of CBP/p300. This protein is aninhibitor of the TGF-beta signal transduction pathway and to be important insuppressing transcriptional activation dependent on the co-activators CBP andp300. Inhibition of NF-kappa B activity is a function of the N-terminaldomain of SNIP1 and involves competition of SNIP1 and the NF-kappa B subunit,RelA/p65, for binding to p300, similar to the mechanism of inhibition of Smadsignaling by SNIP1. |
Application : | SDS-PAGE |
Form : | Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl. |
Molecular Weight : | 18.8 kDa (160aa),confirmed by MALDI-TOF |
Purity : | > 90% by SDS-PAGE |
Concentration : | 1 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHH SSGLVPRGSH MYIIDLGSGNGTFLNNKRIEP QRYYELKEKD VLKFGFSSRE YVLLHESSDT SEIDRKDDED EEEEEEVSDSRWRLYPFKNDEVLPVMYIH RQSAYLLGRH RRIADIPIDH PSCSKQHAVF QYRLVEYTRA DGTVGRRVKP |
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
OfficialSymbol : | SNIP1 |
Gene Name : | SNIP1 Smad nuclear interacting protein1 [ Homo sapiens ] |
Synonyms : | SNIP1; Smad nuclear interacting protein1; FLJ12553; dJ423B22.2; RP3-423B22.3; smadnuclear-interacting protein 1; FHAdomain-containing protein SNIP1; Smadnuclear interacting protein (SNIP1); OTTHUMP00000004404 |
Gene ID : | 79753 |
mRNA Refseq : | NM_024700 |
Protein Refseq : | NP_078976 |
MIM : | 608241 |
UniProt ID : | Q8TAD8 |
Chromosome Location : | 1p34.3 |
Pathway : | Regulation of nuclear SMAD2/3signaling; TGF-beta Receptor Signaling Pathway |
Function : | Protein binding |
Products Types
◆ Recombinant Protein | ||
SNIP1-4184R | Recombinant Rhesus Macaque SNIP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SNIP1-5302R | Recombinant Rat SNIP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SNIP1-3108Z | Recombinant Zebrafish SNIP1 | +Inquiry |
SNIP1-5643R | Recombinant Rat SNIP1 Protein | +Inquiry |
SNIP1-692H | Recombinant Human Smad nuclear interacting protein 1, His-tagged | +Inquiry |
◆ Lysates | ||
SNIP1-1628HCL | Recombinant Human SNIP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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