Recombinant Human GAS6 (Ala31-Ala678), His-tagged

• Cat.No.: GAS6-622H
• Product Overview: A DNA sequence encoding the mature human GAS6 (Ala31-Ala678)isoform 1 with 6 His tag on the N-Terminus was expressed in E.ColiThis protein was purified by Ni-NTA column.

Specification

• Cat. No.: GAS6-622H
• Description: This gene product is a gamma-carboxyglutamic acid(Gla)-containing protein thought to be involved in the stimulation of cellproliferation, and may play a role in thrombosis. Alternatively splicedtranscript variants encoding different isoforms have been found for thisgene.
• Source: E. coli
• Formulation: Lyophilized 100ug human GAS6 in 50ul of, Carry free.
• Application: ELISA
• Molecular Weight: 89.9KDa
• Purity: >90%in SDS-PAGE gel PBS lyophilized.
• Sequence: MatureForm of human GAS6 (Ala31-Ala678)
• Reconstitution: Add500ul deionized water to the vial to prepare a working stock solution at 200ug/mL.Allow to set at least 30 minutes at 4°C, mix well.
• Storage: Storelyophilized protein at -20°C or -70°C. Lyophilized protein is stable for upto 6 months from date of receipt at -20°C to -70°C. Upon reconstitution, thisprotein can be stored at -20°C for a few weeks or at -70°C in a manual defrostfreezer for long term storage (six months). Aliquot reconstituted protein toavoid repeated freezing/thawing cycles.

Gene Information

• Gene Name: GAS6 growth arrest-specific 6 [ Homosapiens ]
• Official Symbol: GAS6
• Synonyms: GAS6; GAS-6; growth arrest-specific 6; AXSF; AXLLG; FLJ34709;DKFZp666G247; growth arrest-specific protein 6; AXL stimulatory factor; AXLreceptor tyrosine kinase ligand; OTTHUMP00000018777
• Gene ID: 2621
• mRNA Refseq: NM_000820
• Protein Refseq: NP_000811
• MIM: 600441
• UniProt ID: Q14393
• Chromosome Location: 13q34
• Pathway: Cellsurface interactions at the vascular wall; Gamma-carboxylation of proteinprecursors; Gamma-carboxylation, transport, and amino-terminal cleavage ofproteins; Hemostasis; Metabolism of proteins; PTM: gamma carboxylation,hypusine formation and arylsulfatase activation; Platelet activation,signaling and aggregation; Platelet degranulation; Post-translational proteinmodification; Removal of aminoterminal propeptides from gamma-carboxylatedproteins; Response to elevated platelet cytosolic Ca2+; Transport ofgamma-carboxylated protein precursors from the endoplasmic reticulum to theGolgi apparatus
• Function: calciumion binding; receptor agonist activity; receptor binding; receptor tyrosinekinase binding