Recombinant Human Small Ubiquitin-related Modifier 1

• Cat.No.: SUMO1-20H
• Product Overview: Recombinanthuman SUMO1was produced by E. coli expression system.

Specification

• Cat. No.: SUMO1-20H
• Description: This geneencodes a protein that is a member of the SUMO (small ubiquitin-likemodifier) protein family. It functions in a manner similar to ubiquitin inthat it is bound to target proteins as part of a post-translationalmodification system. However, unlike ubiquitin which targets proteins fordegradation, this protein is involved in a variety of cellular processes,such as nuclear transport, transcriptional regulation, apoptosis, and proteinstability. It is not active until the last four amino acids of thecarboxy-terminus have been cleaved off. Several pseudogenes have been reportedfor this gene. Alternate transcriptional splice variants encoding differentisoforms have been characterized.
• Source: E. coli
• Species: Human
• Purity: Greater than 95% as determined by SEC-HPLC.Greater than 95% as determined by reducing SDS-PAGE.
• EndotoxinLevel: Less than 0.1 ng/μg (1 IEU/μg).
• Formulation: Lyophilized at 1mg/ml in 20mM PBS
• Reconstitution: Werecommend a quick spin followed by reconstitution of Recombinant Human SUMO1in sterile 18M -cm H2O not less than 100 g/ml, which can then befurther diluted to working solutions.
• Storage: LyophilizedRecombinant Human SUMO1 although stable at room temperature for 3 weeks,should be stored desiccated below -18 C. Upon reconstitution RecombinantHuman SUMO1 should be stored at 4 C between 2-7 days and aliquots ofreconstituted samples are stable up to 3 months below -18 C for future use. Pleaseavoid freeze-thaw cycles.
• OfficialSymbol: SUMO1

Gene Information

• Gene Name: SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) [ Homo sapiens ]
• Synonyms: SUMO1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C;SMT3H3; SUMO-1; UBL1; DAP-1;SUMO1; SMT3 suppressor of mif two 3 homolog 1;sentrin; GAP modifying protein 1; ubiquitin-like 1 (sentrin); GAP-modifyingprotein 1; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1 (S.cerevisiae); SMT3 suppressor of mif two 3 homolog 1 (yeast);Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C;Ubiquitin-like protein UBL1
• Gene ID: 7341
• mRNA Refseq: NM_001005781
• Protein Refseq: NP_001005781
• MIM: 601912
• UniProt ID: P63165
• Chromosome Location: 2q33
• Function: protein binding