Recombinant Human ABCB1, His-tagged ABCB1-2549H

Recombinant Human ABCB1, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human ABCB1, His-tagged

Recombinant Human ABCB1, His-tagged

ABCB1 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : ABCB1-2549H
Product Overview : The protein was expressed as 6*his-tagged fusion protein by E. coli and Purified by Ni-sepharose.
Description : The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Source : E. coli
Antigen PeptideRegion : 624-708aa
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.0) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Storage : The protein is stored in PBS buffer at -20°C. Repeated freeze-thaw cycles should be avoided.
Gene Name : ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 [ Homo sapiens ]
Official Symbol : ABCB1
Synonyms : ABCB1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; MGC163296; multidrug resistance protein 1; P-glycoprotein 1;colchicin sensitivity; doxorubicin resistance; EC 3.6.3.44
Gene ID : 5243
mRNA Refseq : NM_000927
Protein Refseq : NP_000918
MIM : 171050
UniProt ID : P08183
Chromosome Location : 7q21.12
Pathway : ABC transporters; ABC-family proteins mediated transport; Bile secretion; Codeine and morphine metabolism; HIF-1-alpha transcription factor network; Nuclear receptors in lipid metabolism and toxicity; Transmembrane transport of small molecules
Function : ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; hydrolase activity; nucleotide binding; protein binding; transporter activity; xenobiotic-transporting ATPase activity

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy