Recombinant Human PFKFB3, GST-tagged
Cat.No. : | PFKFB3-82912TH |
- Specification
- Gene Information
- Related Products
Cat. No. : | PFKFB3-82912TH |
ProductOverview : | Recombinant human PFKFB3 partial ORF ( 412 a.a. - 520 a.a.) fused with a GST-tag at N-terminal was expressed in wheat germ and purified by Glutathione Sepharose. |
Description : | PFKM is regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. |
Source : | Wheat germ |
MolecularMass : | 37.73 kDa |
AA-Sequence : | CPLHTVLKLTPVAYGCRVESIYLNV ESVCTHRERSEDAKKGPNPLMRRNS VTPLASPEPTKKPRINSFEEHVAST SAALPSCLPPEVPTQLPGQNMKGSR SSADSSRKH |
StorageBuffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer. |
Applications : | ELISA; WB |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Officialsymbol : | PFKFB3 |
Gene Name : | PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Homo sapiens ] |
Synonyms : | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; Renal carcinoma antigen NY-REN-56; FLJ37326; 6PF-2-K/Fru-2,6-P2ase 3; OTTHUMP00000019041; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; OTTHUMP00000019044; iPFK-2; OTTHUMP00000019048; PFK/FBPase 3; PFK2; IPFK2; fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; OTTHUMP00000019052; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; OTTHUMP00000019039; OTTHUMP00000019040; OTTHUMP00000019045; OTTHUMP00000019046; OTTHUMP00000019047; OTTHUMP00000019050 |
Gene ID : | 5209 |
mRNA Refseq : | NM_001145443 |
Protein Refseq : | NP_001138915 |
MIM : | 605319 |
UniProt ID : | Q5VX15 |
Chromosome Location : | 10p15.1 |
Pathway : | AMPK signaling, organism-specific biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem |
Function : | 6-phosphofructo-2-kinase activity; 6-phosphofructo-2-kinase activity; ATP binding; catalytic activity; fructose-2,6-bisphosphate 2-phosphatase activity; hydrolase activity; identical protein binding; kinase activity; nucleotide binding; protein binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
PFKFB3-4052R | Recombinant Rat PFKFB3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKFB3-215H | Recombinant Human PFKFB3, GST-tagged | +Inquiry |
PFKFB3-518H | Active Recombinant Human PFKFB3 Protein, His & GST-tagged | +Inquiry |
PFKFB3-24H | Active Recombinant Human PFKFB3 protein, His-tagged | +Inquiry |
PFKFB3-3284H | Recombinant Human PFKFB3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
PFKFB3-471HCL | Recombinant Human PFKFB3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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