Recombinant Human PFKFB3, GST-tagged
Cat.No. : | PFKFB3-82913TH |
Product Overview : | Recombinant human PFKFB3 isoform 1 (Q16875-1) (Met 1-His 520) fused with a GST-tag at N-terminal was expressed in Baculovirus-Insect cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PFKFB3-82913TH |
Description : | PFKM is regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. |
Source : | Baculovirus-Insect cells |
Species : | Human |
Purity : | >85 % as determined by SDS-PAGE. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
MolecularMass : | The recombinant human PFKFB3 /GST chimera consists of 757 amino acids and has a calculated molecular mass of 87.4 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions. |
Formulation : | Lyophilized from 0.2μm filtered solution of 20mM Tris, 500mM NaCl, pH 7.0, 10%glycerol, 0.3mM DTT |
Storage : | Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C |
Gene Name : | PFKFB3 6-phosphofructo-2-kinase/ fructose-2, 6-biphosphatase 3 [ Homo sapiens ] |
Synonyms : | 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; Renal carcinoma antigen NY-REN-56; FLJ37326; 6PF-2-K/Fru-2,6-P2ase 3; OTTHUMP00000019041; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; OTTHUMP00000019044; iPFK-2; OTTHUMP00000019048; PFK/FBPase 3; PFK2; IPFK2; fructose-6-phosphate, 2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; OTTHUMP00000019039; OTTHUMP00000019040; OTTHUMP00000019045; OTTHUMP00000019046; OTTHUMP00000019047; OTTHUMP00000019050; OTTHUMP00000019052 |
Gene ID : | 5209 |
mRNA Refseq : | NM_001145443.1 |
Protein Refseq : | NP_001138915.1 |
MIM : | 605319 |
UniProt ID : | Q5VX15 |
Chromosome Location : | 10p15.1 |
Pathway : | AMPK signaling; Fructose and mannose metabolism; Fructose and mannose metabolism, conserved biosystem; Glucose metabolism; Glycolysis; HIF-1-alpha transcription factor network |
Function : | 6-phosphofructo-2-kinase activity; 6-phosphofructo-2-kinase activity; ATP binding; catalytic activity; fructose-2,6-bisphosphate 2-phosphatase activity; hydrolase activity; identical protein binding; kinase activity; nucleotide binding; protein binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
PFKFB3-4052R | Recombinant Rat PFKFB3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKFB3-518H | Active Recombinant Human PFKFB3 Protein, His & GST-tagged | +Inquiry |
PFKFB3-3284H | Recombinant Human PFKFB3 protein, His-tagged | +Inquiry |
PFKFB3-4392R | Recombinant Rat PFKFB3 Protein | +Inquiry |
PFKFB3-24H | Active Recombinant Human PFKFB3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
PFKFB3-471HCL | Recombinant Human PFKFB3 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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