"PFKFB3" Related Products


Recombinant Human PFKFB3, GST-tagged

Cat. No.: PFKFB3-82913TH
Product Overview: Recombinant human PFKFB3 isoform 1 (Q16875-1) (Met 1-His 520) fused with a GST-tag at N-terminal was expressed in Baculovirus-Insect cells.
Description: PFKM is regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease.
Source: Baculovirus-Insect cells
Species: Human
Purity: >85 % as determined by SDS-PAGE.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
MolecularMass: The recombinant human PFKFB3 /GST chimera consists of 757 amino acids and has a calculated molecular mass of 87.4 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions.
Formulation: Lyophilized from 0.2μm filtered solution of 20mM Tris, 500mM NaCl, pH 7.0, 10%glycerol, 0.3mM DTT
Storage: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Stability: Samples are stable for up to twelve months from date of receipt at -70°C
Gene Name: PFKFB3 6-phosphofructo-2-kinase/ fructose-2, 6-biphosphatase 3 [ Homo sapiens ]
Synonyms: 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; Renal carcinoma antigen NY-REN-56; FLJ37326; 6PF-2-K/Fru-2,6-P2ase 3; OTTHUMP00000019041; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; OTTHUMP00000019044; iPFK-2; OTTHUMP00000019048; PFK/FBPase 3; PFK2; IPFK2; fructose-6-phosphate, 2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; OTTHUMP00000019039; OTTHUMP00000019040; OTTHUMP00000019045; OTTHUMP00000019046; OTTHUMP00000019047; OTTHUMP00000019050; OTTHUMP00000019052
Gene ID: 5209
mRNA Refseq: NM_001145443.1
Protein Refseq: NP_001138915.1
MIM: 605319
UniProt ID: Q5VX15
Chromosome Location: 10p15.1
Pathway: AMPK signaling; Fructose and mannose metabolism; Fructose and mannose metabolism, conserved biosystem; Glucose metabolism; Glycolysis; HIF-1-alpha transcription factor network
Function: 6-phosphofructo-2-kinase activity; 6-phosphofructo-2-kinase activity; ATP binding; catalytic activity; fructose-2,6-bisphosphate 2-phosphatase activity; hydrolase activity; identical protein binding; kinase activity; nucleotide binding; protein binding; transferase activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.