"CCL11" Related Products

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Recombinant Human Chemokine (C-C motif) Ligand 11, His-tagged

Cat.No. : CCL11-622H
Product Overview : Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10.6 kDa.
Description : CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Molecular Mass : 10.6 kDa (95aa), confirmed by MALDI-TOF
Protein length : 24-97aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP
Endotoxin : < 1.0 eu per 1 micogram of protein (determined by lal
Purity : >90% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : CCL11 chemokine (C-C motif) ligand 11 [ Homo sapiens ]
Official Symbol : CCL11
Synonyms : CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11; small-inducible cytokine A11; eosinophil chemotactic protein; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); SCYA11;
Gene ID : 6356
mRNA Refseq : NM_002986
Protein Refseq : NP_002977
MIM : 601156
UniProt ID : P51671
Chromosome Location : 17q21.1-q21.2
Pathway : Asthma, organism-specific biosystem; Asthma, conserved biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
Function : chemokine activity;

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