Recombinant Human Chemokine (C-C motif) Ligand 11, His-tagged

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Recombinant Human Chemokine (C-C motif) Ligand 11, His-tagged

CCL11 Related Products

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Cat.No. : CCL11-622H
Product Overview : Recombinant CCL11 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10.6 kDa.
Description : CCL11 is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Molecular Mass : 10.6 kDa (95aa), confirmed by MALDI-TOF
Protein length : 24-97aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP
Endotoxin : < 1.0 eu per 1 micogram of protein (determined by lal
Purity : >90% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : CCL11 chemokine (C-C motif) ligand 11 [ Homo sapiens ]
Official Symbol : CCL11
Synonyms : CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11; small-inducible cytokine A11; eosinophil chemotactic protein; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); SCYA11;
Gene ID : 6356
mRNA Refseq : NM_002986
Protein Refseq : NP_002977
MIM : 601156
UniProt ID : P51671
Chromosome Location : 17q21.1-q21.2
Pathway : Asthma, organism-specific biosystem; Asthma, conserved biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;
Function : chemokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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