Recombinant Human Cbp/P300-Interacting Transactivator, With Glu/Asp-Rich Carboxy-Terminal Domain, 2, His-tagged
Cat.No. : | CITED2-6919H |
Product Overview : | Recombinant CITED2 protein, fused to His-tagged, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 29.5 kDa. |
- Specification
- Gene Information
- Related Products
Description : | CITED2 is an important transcriptional cofactor involved in multiple organ development. It is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor (HIF)-1a through its competitive binding with HIF-1a to CBP/p300. CITED2 is necessary for mouse fetal liver hematopoiesis and is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 50% glycerol, 1mM DTT. |
Molecular Mass : | 29.5 kDa (278 aa), confirmed by MALDI-TOF. |
Protein length : | 1-270aa |
AA Sequence : | MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH |
Endotoxin : | < 1.0 eu per 1 μg of protein (determined by lal |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ] |
Official Symbol : | CITED2 |
Synonyms : | CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; cbp/p300-interacting transactivator 2; MRG1; MRG-1; MSG1-related gene 1; MSG-related protein 1; melanocyte-specific gene 1-related gene 1; ASD8; VSD2; P35SRJ; |
Gene ID : | 10370 |
mRNA Refseq : | NM_001168388 |
Protein Refseq : | NP_001161860 |
MIM : | 602937 |
UniProt ID : | Q99967 |
Chromosome Location : | 6q23.3 |
Pathway : | HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; |
Function : | LBD domain binding; RNA polymerase II activating transcription factor binding; SMAD binding; chromatin binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; transcription corepressor activity; |
Products Types
◆ Recombinant Protein | ||
CITED2-606H | Recombinant Human CITED2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cited2-2169M | Recombinant Mouse Cited2 Protein, Myc/DDK-tagged | +Inquiry |
CITED2-3247H | Recombinant Human CITED2 Protein, MYC/DDK-tagged | +Inquiry |
CITED2-1387H | Recombinant Human CITED2 Protein, GST-tagged | +Inquiry |
CITED2-1702M | Recombinant Mouse CITED2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CITED2-359HCL | Recombinant Human CITED2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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