Recombinant Full Length Human CITED2 Protein, C-Flag-tagged

• Cat.No.: CITED2-1582HFL
• Product Overview: Recombinant Full Length Human CITED2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.9 kDa
• AA Sequence: MADHMMAMNHGRFPDGTNGLHHHPA HRMGMGQFPSPHHHQQQQPQHAFNA LMGEHIHYGAGNMNATSGIR HAMGPGTVNGGHPPSALAPAARFNN SQFMGPPVASQGGSLPASMQLQKLN NQYFNHHPYPHNHYMPDLHP AAGHQMNGTNQHFRDCNPKHSGGSS TPGGSGGSSTPGGSGSSSGGGAGSS NSGGGSGSGNMPASVAHVPA
  AMLPPNVIDTDFIDEEVLMSLVIEM GLDRIKELPELWLGQNEFDFMTDFV CKQQPSRVSCTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [ Homo sapiens (human) ]
• Official Symbol: CITED2
• Synonyms: ASD8; MRG1; VSD2; MRG-1; P35SRJ
• Gene ID: 10370
• mRNA Refseq: NM_001168388.3
• Protein Refseq: NP_001161860.1
• MIM: 602937
• UniProt ID: Q99967