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Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 1 (rho family, small GTP binding protein Rac1), His-tagged

Cat.No.: RAC1-6911H
Product Overview: Recombinant human RAC1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 23.6 kDa.
Description: RAC1 belonging to the Rho small GTPase family, regulates the actin cytoskeleton but also other cellular processes. RAC1 have been shown to be involved in the regulation of cell-cell adhesion.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 1 mM DTT, 1 mM EDTA, 10% glycerol.
Molecular Mass: 23.6 kDa (212aa), confirmed by MALDI-TOF
Protein length: 1-192aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPNTPI ILVGTKLDLR DDKDTIEK LK EKKLTPITYP QGLAMAKEIG AVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKRKRKCL LL
Endotoxin: < 1.0 eu per 1 micogram of protein (determined by lal
Purity: >95% by SDS-PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [ Homo sapiens ]
Official Symbol: RAC1
Synonyms: RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1; p21 Rac1; Rac 1; TC 25; ras-like protein TC25; cell migration-inducing gene 5 protein; MIG5; Rac-1; TC-25; p21-Rac1; MGC111543;
Gene ID: 5879
mRNA Refseq: NM_006908
Protein Refseq: NP_008839
MIM: 602048
UniProt ID: P63000
Chromosome Location: 7p22
Pathway: Activation of Rac, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;
Function: GTP binding; GTPase activity; enzyme binding; nucleotide binding; protein binding; thioesterase binding;

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