"ATOX1" Related Products

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Recombinant Human ATX1 Antioxidant Protein 1 Homolog (yeast), His-tagged

Cat.No.: ATOX1-6909H
Product Overview: Recombinant human ATOX1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 9.5 kDa.
Description: Copper transport protein ATOX1, also known as HAH1, a metal transport protein that belongs to the ATX1 family. ATOX1 is involved in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
Molecular Mass: 9.5 kDa (88aa), confirmed by MALDI-TOF
Protein length: 1-68aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MPKHEFSVDM TC GGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE
Purity: >95% by SDS-PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ]
Official Symbol: ATOX1
Synonyms: ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1 (antioxidant protein 1, yeast) homolog 1; copper transport protein ATOX1; HAH1; metal transport protein ATX1; ATX1; MGC138453; MGC138455;
Gene ID: 475
mRNA Refseq: NM_004045
Protein Refseq: NP_004036
MIM: 602270
UniProt ID: O00244
Chromosome Location: 5q32
Pathway: Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem;
Function: copper chaperone activity; copper ion binding; copper-dependent protein binding; metal ion binding; metallochaperone activity;

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