Recombinant Human Protein Kinase (cAMP-dependent, catalytic) Inhibitor Beta, His-tagged

• Cat.No.: PKIB-2502H
• Product Overview: Recombinant human PKIB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 10.6 kDa.

Specification

• Description: PKIB, also known as cAMP-dependent protein kinase inhibitor beta, is a member of the cAMP-dependent protein kinase inhibitor family. This protein may interact with the catalytic subunit of cAMP-dependent protein kinase and act as a competitive inhibitor. At least three alternatively spliced transcript variants encoding the same protein have been reported.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT.
• Molecular Mass: 10.6 kDa (98aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Protein length: 1-78aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MRTDSSKMTD VESGVANFAS SARAGRRNAL PDIQSSAATD GTSDLPLKLE ALSVKEDAKE KDEKTTQDQL EKPQNEEK
• Purity: >90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta [ Homo sapiens ]
• Official Symbol: PKIB
• Synonyms: PKIB; protein kinase (cAMP-dependent, catalytic) inhibitor beta; PRKACN2; cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2; FLJ23817
• Gene ID: 5570
• mRNA Refseq: NM_032471
• Protein Refseq: NP_115860
• MIM: 606914
• UniProt ID: Q9C010
• Chromosome Location: 6q21-q22.1
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem
• Function: cAMP-dependent protein kinase inhibitor activity; protein kinase inhibitor activity