"ARL14" Related Products

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Recombinant Human ADP-Ribosylation Factor-Like 14, His-tagged

Cat.No.: ARL14-2489H
Product Overview: Recombinant human ARL14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 23.8 kDa.
Description: ARL14 is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein family of Ras-related GTPases. MHC class II molecules present peptides to T helper cells to facilitate immune responses and are strongly linked to autoimmune diseases. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 40% glycerol, 200mM NaCl, 1mM EDTA.
Molecular Mass: 23.8kDa (212aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Protein length: 1-192aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25mg/ml (determined by Bradford assay)
Gene Name: ARL14 ADP-ribosylation factor-like 14 [ Homo sapiens ]
Official Symbol: ARL14
Synonyms: ARL14; ADP-ribosylation factor-like 14; ADP ribosylation factor 7 , ARF7; ADP-ribosylation factor-like protein 14; FLJ22595; ADP-ribosylation factor 7; ARF7;
Gene ID: 80117
mRNA Refseq: NM_025047
Protein Refseq: NP_079323
MIM: 614439
UniProt ID: Q8N4G2
Chromosome Location: 3q25.33
Function: GTP binding; nucleotide binding; protein binding;

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