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Recombinant Human PTEN Induced Putative Kinase 1

Cat.No. : PINK1-1347H
Product Overview : Recombinant human PINK protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 37.9 kDa.
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  • Gene Information
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Description : PINK1 is a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this protein cause one form of autosomal recessive early-onset Parkinson disease.
Source : E. coli
Species : Human
Tag : N/A
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) 1M Urea, 5% Glycerol.
Molecular Mass : 37.9 kDa (353aa)
Protein length : 156-507aa
AA Sequence : MYLIGQSIGK GCSAAVYEAT MPTLPQNLEV TKSTGLLPGR GPGTSAPGEG QERAPGAPAF PLAIKMMWNI SAGSSSEAIL NTMSQELVPA SRVALAGEYG AVTYRKSKRG PKQLAPHPNI IRVLRAFTSS VPLLPGALVD YPDVLPSRLH PEGLGHGRTL FLVMKNYPCT LRQYLCVNTP SPRLAAMMLL QLLEGVDHLV QQGIAHRDLK SDNILVELDP DGCPWLVIAD FGCCLADESI GLQLPFSSWY VDRGGNGCLM APEVSTARPG PRAVIDYSKA DAWAVGAIAY EIFGLVNPFY GQGKAHLESR SYQEAQLPAL PESVPPDVRQ LVRALLQREA SKRPSARVAA NVL
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : PINK1 PTEN induced putative kinase 1 [ Homo sapiens ]
Official Symbol : PINK1
Synonyms : PINK1; PTEN induced putative kinase 1; PARK6, Parkinson disease (autosomal recessive) 6; serine/threonine-protein kinase PINK1, mitochondrial; protein kinase BRPK; PTEN-induced putative kinase protein 1; BRPK; PARK6; FLJ27236;
Gene ID : 65018
mRNA Refseq : NM_032409
Protein Refseq : NP_115785
MIM : 608309
UniProt ID : Q9BXM7
Chromosome Location : 1p36.12
Pathway : Parkinsons disease, organism-specific biosystem;
Function : ATP binding; C3HC4-type RING finger domain binding; calcium-dependent protein kinase activity; kinase activity; magnesium ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; ubiquitin protein ligase binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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