Recombinant Human Serglycin, His-tagged
Cat.No. : | SRGN-6884H |
Product Overview : | Recombinant human SRGN protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 17.4 kDa. |
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- Gene Information
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Description : | SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl. |
Molecular Mass : | 17.4 kDa (156aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). |
Protein length : | 28-158aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMYPTRR ARYQWVRCNP DSNSANCLEE KGPMFELLPG ESNKIPRLRT DLFPKTRIQD LNRIFPLSED YSGSGFGSGS GSGSGSGSGF LTEMEQDYQL VDESDAFHDN LRSLDRNLPS DSQDLGQHGL EEDFML |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford) |
Gene Name : | SRGN serglycin [ Homo sapiens ] |
Official Symbol : | SRGN |
Synonyms : | SRGN; serglycin; PRG, PRG1, proteoglycan 1, secretory granule; PPG; serglycin proteoglycan; p.PG; proteoglycan 1, secretory granule; platelet proteoglycan core protein; hematopoetic proteoglycan core peptide; hematopoetic proteoglycan core protein; secretory granule proteoglycan core peptide; secretory granule proteoglycan core protein; proteoglycan protein core for mast cell secretory granule; PRG; PRG1; MGC9289; FLJ12930; |
Gene ID : | 5552 |
mRNA Refseq : | NM_002727 |
Protein Refseq : | NP_002718 |
MIM : | 177040 |
UniProt ID : | P10124 |
Chromosome Location : | 10q22.1 |
Pathway : | Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem; |
Function : | collagen binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SRGN-2734H | Recombinant Human SRGN Protein, His-tagged | +Inquiry |
Srgn-2104R | Recombinant Rat Srgn Protein, His&GST-tagged | +Inquiry |
SRGN-2836H | Recombinant Human SRGN Protein, His-tagged, OVA Conjugated | +Inquiry |
SRGN-5400R | Recombinant Rat SRGN Protein, His (Fc)-Avi-tagged | +Inquiry |
SRGN-8716M | Recombinant Mouse SRGN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SRGN-1119HCL | Recombinant Human SRGN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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