Recombinant Human Thymidine Kinase 1, Soluble, His-tagged
Cat.No. : | TK1-1342H |
Product Overview : | Recombinant human TK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | TK1 is an enzyme, a phosphotransferase (a kinase): 2"-deoxythymidine kinase, ATP-thymidine 5"-phosphotransferase. It is present in two forms in mammalian cells, TK1 and TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT. |
Molecular Mass : | 28.0 kDa (258aa) confirmed by MALDI-TOF |
Protein length : | 1-234aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMSCINL PTVLPGSPSK TRGQIQVILG PMFSGKSTEL MRRVRRFQIA QYKCLVIKYA KDTRYSSSFC THDRNTMEAL PACLLRDVAQ EALGVAVIGI DEGQFFPDIV EFCEAMANAG KTVIVAALDG TFQRKPFGAI LNLVPLAESV VKLTAVCMEC FREAAYTKRL GTEKEVEVIG GADKYHSVCR LCYFKKASGQ PAGPDNKENC PVPGKPGEAV AARKLFAPQQ ILQCSPAN |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -72°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | TK1 thymidine kinase 1, soluble [ Homo sapiens ] |
Official Symbol : | TK1 |
Synonyms : | TK1; thymidine kinase 1, soluble; thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform; TK2; |
Gene ID : | 7083 |
mRNA Refseq : | NM_003258 |
Protein Refseq : | NP_003249 |
MIM : | 188300 |
UniProt ID : | P04183 |
Chromosome Location : | 17q23.2-q25.3 |
Pathway : | Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; |
Function : | ATP binding; kinase activity; metal ion binding; nucleoside kinase activity; nucleotide binding; thymidine kinase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
TK1-9H | Recombinant Human TK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TK1-8093H | Recombinant Human TK1 protein, His & GST-tagged | +Inquiry |
TK1-10208Z | Recombinant Zebrafish TK1 | +Inquiry |
TK1-3247H | Recombinant Human TK1, His-tagged | +Inquiry |
TK1-31518TH | Recombinant Human TK1, His-tagged | +Inquiry |
◆ Lysates | ||
TK1-1783HCL | Recombinant Human TK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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