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Recombinant Human Ovarian Tumor Suppressor Candidate 2, His-tagged

Cat.No. : OVCA2-6939H
Product Overview : Recombinant human OVCA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Description : OVCA2 belongs to the UPF0483 family. It is ubiquitously expressed and its expression is regulated by retinoids. OVCA2 interacts with apoptosis-related protein Bag-1, indicating that this protein may participate in cell proliferation. Due to its structural and catalytic characteristics, OVCA2 is thought to act as a serine-hydrolase and, because of its reduced expression in ovarian and other tumor cell lines, it may play a role in tumor suppression.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT.
Molecular Mass : 26.9 kDa (251aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Protein length : 1-227aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMAAQRP LRVLCLAGFR QSERGFREKT GALRKALRGR AELVCLSGPH PVPDPPGPEG ARSDFGSCPP EEQPRGWWFS EQEADVFSAL EEPAVCRGLE ESLGMVAQAL NRLGPFDGLL GFSQGAALAA LVCALGQAGD PRFPLPRFIL LVSGFCPRGI GFKESILQRP LSLPSLHVFG DTDKVIPSQE SVQLASQFPG AITLTHSGGH FIPAAAPQRQ AYLKFLDQFA E
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : OVCA2 ovarian tumor suppressor candidate 2 [ Homo sapiens ]
Official Symbol : OVCA2
Synonyms : OVCA2; ovarian tumor suppressor candidate 2; ovarian cancer-associated gene 2 protein; candidate tumor suppressor in ovarian cancer 2; ovarian cancer gene-2 protein;
Gene ID : 124641
mRNA Refseq : NM_080822
Protein Refseq : NP_543012
MIM : 607896
UniProt ID : Q8WZ82
Chromosome Location : 17p13.3
Function : hydrolase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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