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Active Recombinant Human CAT Protein, His-tagged, Animal Free, Beta-lactam Antibiotics Free

Cat.No. : CAT-2514H
Product Overview : Recombinant Human CAT Protein with His tag was produced in E. coli and was produced in Animal Free and Beta-lactam Antibiotics Free conditions.
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Description : This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Source : E. coli
Species : Human
Tag : His
Bio-activity : Measured by its ability to degrade hydrogen peroxide using Invitrogen AmplexTM Red Catalase Assay Kit (Cat# A22180). The specific activity is 181 KU/mg
Molecular Mass : 61.9 kDa
AA Sequence : MGSSHHHHHHSSGLVPRGSHMADSR DPASDQMQHWKEQRAAQKADVLTTG AGNPVGDKLNVITVGPRGPLLVQDV VFTDEMAHFDRERIPERVVHAKGAG AFGYFEVTHDITKYSKAKVFEHIGK KTPIAVRFSTVAGESGSADTVRDPR GFAVKFYTEDGNWDLVGNNTPIFFI RDPILFPSFIHSQKRNPQTHLKDPD MVWDFWSLRPESLHQVSFLFSDRGI PDGHRHMNGYGSHTFKLVNANGEAV YCKFHYKTDQGIKNLSVEDAARLSQ EDPDYGIRDLFNAIATGKYPSWTFY IQVMTFNQAETFPFNPFDLTKVWPH KDYPLIPVGKLVLNRNPVNYFAEVE QIAFDPSNMPPGIEASPDKMLQGRL FAYPDTHRHRLGPNYLHIPVNCPYR ARVANYQRDGPMCMQDNQGGAPNYY PNSFGAPEQQPSALEHSIQYSGEVR RFNTANDDNVTQVRAFYVNVLNEEQ RKRLCENIAGHLKDAQIFIQKKAVK NFTEVHPDYGSHIQALLDKYNAEKP KNAIHTFVQSGSHLAAREKANL
Purity : > 90% by SDS-PAGE
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 1.66 mg/mL
Storage Buffer : 20mM Tris, 150mM NaCl, 10% glycerol, pH 8.0
Publication :
Silica nanoparticle with a single His-tag for addressable functionalization, reversible assembly, and recycling. (2017)
Silica nanoparticle with a single His-tag for addressable functionalization, reversible assembly, and recycling (2018)
Gene Name : CAT catalase [ Homo sapiens (human) ]
Official Symbol : CAT
Synonyms : CAT; catalase; MGC138422; MGC138424;
Gene ID : 847
mRNA Refseq : NM_001752
Protein Refseq : NP_001743
MIM : 115500
UniProt ID : P04040

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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