"HOPX" Related Products

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Recombinant Human HOP Homeobox, His-tagged

Cat.No.: HOPX-6951H
Product Overview: Recombinant human HOPX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Description: HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. This protein prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
Molecular Mass: 10.8 kDa (97aa), confirmed by MALDI-TOF
Protein length: 1-73aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSAETA SGPTEDQVEI LEYNFNKVDK HPDSTTLCLI AAEAGLSEEE TQKWFKQRLA KWRRSEGLPS ECRSVTD
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: HOPX HOP homeobox [ Homo sapiens ]
Official Symbol: HOPX
Synonyms: HOPX; HOP homeobox; homeodomain-only protein; homeobox only domain; HOP; LAGY; NECC1; OB1; SMAP31; odd homeobox 1 protein; odd homeobox protein 1; lung cancer-associated Y protein; not expressed in choriocarcinoma clone 1; not expressed in choriocarcinoma protein 1; HOD; TOTO; CAMEO; MGC20820;
Gene ID: 84525
mRNA Refseq: NM_001145459
Protein Refseq: NP_001138931
MIM: 607275
UniProt ID: Q9BPY8
Chromosome Location: 4q12
Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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