Recombinant Human HOP Homeobox, His-tagged
Cat.No. : | HOPX-6951H |
Product Overview : | Recombinant human HOPX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. This protein prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol. |
Molecular Mass : | 10.8 kDa (97aa), confirmed by MALDI-TOF |
Protein length : | 1-73aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMSAETA SGPTEDQVEI LEYNFNKVDK HPDSTTLCLI AAEAGLSEEE TQKWFKQRLA KWRRSEGLPS ECRSVTD |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | HOPX HOP homeobox [ Homo sapiens ] |
Official Symbol : | HOPX |
Synonyms : | HOPX; HOP homeobox; homeodomain-only protein; homeobox only domain; HOP; LAGY; NECC1; OB1; SMAP31; odd homeobox 1 protein; odd homeobox protein 1; lung cancer-associated Y protein; not expressed in choriocarcinoma clone 1; not expressed in choriocarcinoma protein 1; HOD; TOTO; CAMEO; MGC20820; |
Gene ID : | 84525 |
mRNA Refseq : | NM_001145459 |
Protein Refseq : | NP_001138931 |
MIM : | 607275 |
UniProt ID : | Q9BPY8 |
Chromosome Location : | 4q12 |
Function : | sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
HOPX-2545R | Recombinant Rat HOPX Protein, His (Fc)-Avi-tagged | +Inquiry |
HOPX-4934H | Recombinant Human HOPX Protein, GST-tagged | +Inquiry |
HOPX-4273M | Recombinant Mouse HOPX Protein, His (Fc)-Avi-tagged | +Inquiry |
Hopx-3431M | Recombinant Mouse Hopx Protein, Myc/DDK-tagged | +Inquiry |
HOPX-2890R | Recombinant Rat HOPX Protein | +Inquiry |
◆ Lysates | ||
HOPX-5432HCL | Recombinant Human HOPX 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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