Recombinant Human CAMK4 (Active), GST-tagged

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Recombinant Human CAMK4 (Active), GST-tagged

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Cat.No. : CAMK4-1373H
Product Overview : Recombinant full-length human CAMK4 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Description : CAMK4 is a multifunctional serine/threonine protein kinase and a member of Ca(2+)/calmodulin-dependent protein kinase family. CAMK4 is localized in neurons in the hippocampus, amygdala, anterior cingulate cortex, somatosensory cortex, and insular cortex. CAMK4 is involved in neural activity-dependent signaling in the neuronal nucleus and thought to plays an important role in the consolidation/retention of hippocampus-dependent long-term memory.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Bio-activity : 92 nmol/min/mg
Molecular Mass : ~79 kDa
Protein length : Full length
Purity : >85%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : CAMK4 calcium/calmodulin-dependent protein kinase IV [ Homo sapiens ]
Official Symbol : CAMK4
Synonyms : CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV; brain Ca++ calmodulin dependent protein kinase type IV; calcium/calmodulin dependent protein kinase type IV catalytic chain; CAM kinase IV; CAM kinase GR; CaMK GR; caM kinase-GR; CAM kinase- GR; brain Ca++-calmodulin-dependent protein kinase type IV; brain Ca(2+)-calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain; IV; caMK; CaMK IV; CaMK-GR; MGC36771;
Gene ID : 814
mRNA Refseq : NM_001744
Protein Refseq : NP_001735
MIM : 114080
UniProt ID : Q16566
Chromosome Location : 5q21-q23
Pathway : Activation of CaMK IV, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; CREB phosphorylation through the activation of CaMKK, organism-specific biosystem; Ca-dependent events, organism-specific biosystem; CaM pathway, organism-specific biosystem;
Function : ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding;

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