Active Recombinant Human CSK, GST-tagged
Cat.No. : | CSK-1394H |
Product Overview : | Recombinant full-length human CSK was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | CSK is a cytoplasmic tyrosine kinase that has been shown to downregulate the tyrosine kinase activity of the c-src through tyrosine phosphorylation of the c-src carboxy terminus. A yeast 2-hybrid system has been used to identify proteins associated with CSK. The Src homology-3 (SH3) domain of CSK associates with a proline-rich region of PEP, a protein-tyrosine phosphatase expressed in hemopoietic cells. This association is highly specific and it is speculated that PEP may be an effector and/or regulator of CSK in T cells and other hemopoietic cells. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 425 nmol/min/mg |
Molecular Mass : | ~78 kDa |
Protein length : | Full length |
Purity : | >85% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | CSK c-src tyrosine kinase [ Homo sapiens ] |
Official Symbol : | CSK |
Synonyms : | CSK; c-src tyrosine kinase; tyrosine-protein kinase CSK; C-Src kinase; protein-tyrosine kinase CYL; MGC117393; |
Gene ID : | 1445 |
mRNA Refseq : | NM_001127190 |
Protein Refseq : | NP_001120662 |
MIM : | 124095 |
UniProt ID : | P41240 |
Chromosome Location : | 15q24.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; |
Function : | ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein C-terminus binding; protein binding; protein phosphatase binding; protein tyrosine kinase activity; protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
CSK-342H | Active Recombinant Human CSK Protein, GST-tagged | +Inquiry |
CSK-0765H | Recombinant Human CSK Protein (M1-L450), GST tagged | +Inquiry |
CSK-3222M | Recombinant Mouse CSK protein(Met1-Leu450) | +Inquiry |
CSK-882R | Recombinant Rhesus Macaque CSK Protein, His (Fc)-Avi-tagged | +Inquiry |
CSK-1979H | Recombinant Human CSK Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
CSK-27872TH | Native Human CSK | +Inquiry |
◆ Lysates | ||
CSK-628HCL | Recombinant Human CSK cell lysate | +Inquiry |
CSK-001MCL | Recombinant Mouse CSK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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