Active Recombinant Human MINK1, GST-tagged
Cat.No. : | MINK1-1431H |
Product Overview : | Recombinant human MINK1 (1-320) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival. Overexpression of kinase-dead mutants of MINK1 leads to enhanced cell spreading, actin stress fiber formation, adhesion to extracellular matrix and decreased cell motility and invasion. MINK is activated after Ras induction via a mechanism involving reactive oxygen species and mediates stimulation of p38 MAPK downstream of the Raf/ERK pathway. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 19 nmol/min/mg |
Molecular Mass : | ~61 kDa |
Protein length : | 1-320 aa |
Purity : | >90% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | MINK1 misshapen-like kinase 1 [ Homo sapiens ] |
Official Symbol : | MINK1 |
Synonyms : | MINK1; misshapen-like kinase 1; misshapen like kinase 1 (zebrafish); B55; MAP4K6; MINK; misshapen/NIK related kinase; YSK2; ZC3; MEKKK 6; MEK kinase kinase 6; GCK family kinase MINK; misshapen/NIK-related kinase; MAPK/ERK kinase kinase kinase 6; serine/threonine protein kinase; mitogen-activated protein kinase kinase kinase kinase 6; hMINK; hMINKbeta; MGC21111; |
Gene ID : | 50488 |
mRNA Refseq : | NM_001024937 |
Protein Refseq : | NP_001020108 |
MIM : | 609426 |
UniProt ID : | Q8N4C8 |
Chromosome Location : | 17p13.2 |
Pathway : | Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; |
Function : | ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; small GTPase regulator activity; |
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◆ Recombinant Protein | ||
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MINK1-1078H | Recombinant Human MINK1 Protein (M1-G314), Tag Free | +Inquiry |
MINK1-1353H | Recombinant Human MINK1 Protein, MYC/DDK-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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