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Active Recombinant Human PIK3C2G, GST-tagged

Cat.No. : PIK3C2G-1453H
Product Overview : Recombinant human PIK3C2G (468-1203) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
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Description : PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family which plays main roles in signaling pathways and involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions and the N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 280 nmol/min/mg
Molecular Mass : ~110 kDa
Protein length : 468-1203 aa
Purity : >75%
Applications : Kinase Assay, Western Blot
Storage : Store at–70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : PIK3C2G phosphoinositide-3-kinase, class 2, gamma polypeptide [ Homo sapiens ]
Official Symbol : PIK3C2G
Synonyms : PIK3C2G; phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phosphoinositide 3-kinase-C2-gamma; phosphatidylinositol 3-kinase C2 domain-containing gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; PI3K-C2GAMMA; MGC163149;
Gene ID : 5288
mRNA Refseq : NM_004570
Protein Refseq : NP_004561
MIM : 609001
UniProt ID : O75747
Chromosome Location : 12p12
Pathway : 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Insulin Signaling, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Phosphatidylinositol signaling system, organism-specific biosystem;
Function : 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; binding; nucleotide binding; phosphatidylinositol binding; phosphatidylinositol phosphate kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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