"PIK3C2G" Related Products

Recombinant Human PIK3C2G (Active), GST-tagged

Cat.No.: PIK3C2G-1453H
Product Overview: Recombinant human PIK3C2G (468-1203) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family which plays main roles in signaling pathways and involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions and the N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 280 nmol/min/mg
Molecular Mass: ~110 kDa
Protein length: 468-1203 aa
Purity: >75%
Applications: Kinase Assay, Western Blot
Storage: Store at–70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: PIK3C2G phosphoinositide-3-kinase, class 2, gamma polypeptide [ Homo sapiens ]
Official Symbol: PIK3C2G
Synonyms: PIK3C2G; phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phosphoinositide 3-kinase-C2-gamma; phosphatidylinositol 3-kinase C2 domain-containing gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; PI3K-C2GAMMA; MGC163149;
Gene ID: 5288
mRNA Refseq: NM_004570
Protein Refseq: NP_004561
MIM: 609001
UniProt ID: O75747
Chromosome Location: 12p12
Pathway: 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Insulin Signaling, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Phosphatidylinositol signaling system, organism-specific biosystem;
Function: 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; binding; nucleotide binding; phosphatidylinositol binding; phosphatidylinositol phosphate kinase activity;

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