Active Recombinant Human PIP5K1B, GST-tagged

• Cat.No.: PIP5K1B-1461H
• Product Overview: Recombinant full-length human PIP5K1B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: PIP5K1B (phosphatidylinositol-4-phosphate 5-kinase, type I, beta) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. PIP5K1B gene contains 17 exons and spans more than 300 kb. The seventeenth exon was found by RT-PCR, and are derived from the 3-prime untranslated region of the PRKACG gene which is located on 9q13 approximately 3 kb downstream of the STM7.I 3-prime untranslated region.The overexpression of PIP5K1B in COS-7 cells induces an increase in short actin fibers and a decrease in actin stress fibers(2).
• Source: Sf9 Cells
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 220 nmol/min/mg
• Molecular Mass: ~96 kDa
• Protein length: Full length
• Purity: >70%
• Applications: Kinase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta [ Homo sapiens ]
• Official Symbol: PIP5K1B
• Synonyms: PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase, type I, beta; phosphatidylinositol 4-phosphate 5-kinase type-1 beta; MSS4; STM7; PIP5KIbeta; PIP5K1-beta; protein STM-7; ptdIns(4)P-5-kinase 1 beta; phosphatidylinositol 4-phosphate 5-kinase type I beta; phosphatidylinositol-4-phosphate 5-kinase type-1 beta; type I phosphatidylinositol 4-phosphate 5-kinase beta; type I phosphatidylinositol-4-phosphate 5-kinase beta
• Gene ID: 8395
• mRNA Refseq: NM_003558
• Protein Refseq: NP_003549
• MIM: 602745
• UniProt ID: O14986
• Chromosome Location: 9q13
• Pathway: 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Endocytosis, organism-specific biosystem
• Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; nucleotide binding; protein binding; transferase activity