"SRMS" Related Products

Recombinant Human SRMS (Active), GST-tagged

Cat.No. : SRMS-1485H
Product Overview : Recombinant human SRMS (215-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : SRMS is a Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites that is involved in proliferation or differentiation of keratinocytes in the skin. SRMS functions as a rapid downstream signaling intermediate following calcium-induced differentiation in keratinocytes. SRMS constitutes a new family of non-receptor tyrosine kinases that may be redundant in function. SRMS can act either in the membrane or at the nucleus, and may change localization patterns depending on external stimuli.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 24 nmol/min/mg
Molecular Mass : ~54 kDa
Protein length : 215 aa-end
Purity : >95%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [ Homo sapiens ]
Official Symbol : SRMS
Synonyms : SRMS; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; C20orf148, chromosome 20 open reading frame 148; tyrosine-protein kinase Srms; dJ697K14.1; SRM; C20orf148;
Gene ID : 6725
mRNA Refseq : NM_080823
Protein Refseq : NP_543013
UniProt ID : Q9H3Y6
Chromosome Location : 20q13.33
Pathway : Focal Adhesion, organism-specific biosystem;
Function : ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding;

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