"DUSP22" Related Products


Recombinant Human DUSP22 (Active), GST-tagged

Cat.No. : DUSP22-1514H
Product Overview : Recombinant full length human DUSP22 was expressed in E.coli cells using a N-terminal GST tag.
Description : Dual specificity phosphatases (DUSP) family, which can dephosphorylate both phosphoserine/threonine and phosphotyrosine residues, comprise of two subgroups: "typical" DUSP (include 11 MKPs that dephosphorylate the mitogen-activated protein kinases Erk, Jnk, and p38 at their dually phosphorylated TXY activation loop motif) and "atypical" DUSP (include 8 enzymes that lack specific MAP kinase-targeting motifs and tend to be much smaller proteins, which are less than 250 amino acid residues).DUSP22, also called JKAP, JSP1 and MKPX plays a role in various inflammatory and proliferative disorders associated with dysfunctional Jnk signaling.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 20mM MOPS, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 30% glycerol.
Bio-activity : 600 nmol/min/mg
Molecular Mass : ~43 kDa
Protein length : Full length
Purity : >90%
Applications : Phosphatase Assay, Western Blot
Storage : Store at–70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : DUSP22 dual specificity phosphatase 22 [ Homo sapiens ]
Official Symbol : DUSP22
Synonyms : DUSP22; dual specificity phosphatase 22; dual specificity protein phosphatase 22; JKAP; JSP1; MKPX; VHX; JSP-1; MKP-x; LMW-DSP2; MAP kinase phosphatase x; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; mitogen-activated protein kinase phosphatase x; low molecular weight dual specificity phosphatase 2; homolog of mouse dual specificity phosphatase LMW-DSP2; LMWDSP2; FLJ35864;
Gene ID : 56940
mRNA Refseq : NM_020185
Protein Refseq : NP_064570
UniProt ID : Q9NRW4
Chromosome Location : 6pter-q22.33
Pathway : MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem;
Function : hydrolase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;

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