Recombinant Human PRMT3, GST-tagged
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Cat.No. : | PRMT3-6961H |
Product Overview : | Recombinant full-length human PRMT3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | PRMT3 is a protein arginine methyltransferase that catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins. 40S ribosomal protein S2 is a physiological substrate of PRMT3 and PRMT3 regulates ribosome biosynthesis at a stage beyond pre-rRNA processing. DAL-1 (differentially expressed in adenocarcinoma of the lung)/4.1B is a tumor suppressor gene that can significantly inhibits PRMT3 methylation of cellular substrates. Modulation of post-translational methylation may be an important mechanism through which DAL-1/4.1B affects tumor cell growth. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~97 kDa |
Protein length : | Full length |
Purity : | >90% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μ |
Gene Name : | PRMT3 protein arginine methyltransferase 3 [ Homo sapiens ] |
Official Symbol : | PRMT3 |
Synonyms : | PRMT3; protein arginine methyltransferase 3; HMT1 hnRNP methyltransferase like 3 (S. cerevisiae) , HRMT1L3; protein arginine N-methyltransferase 3; HMT1 hnRNP methyltransferase-like 3; heterogeneous nuclear ribonucleoprotein methyltransferase-like 3; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HRMT1L3; |
Gene ID : | 10196 |
mRNA Refseq : | NM_001145166 |
Protein Refseq : | NP_001138638 |
MIM : | 603190 |
UniProt ID : | O60678 |
Chromosome Location : | 11p15.1 |
Function : | metal ion binding; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; transferase activity; zinc ion binding; |
◆ Recombinant Protein
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Prmt3-5132M | Recombinant Mouse Prmt3 Protein, Myc/DDK-tagged | +Inquiry |
PRMT3-097H | Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
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◆ Assay kits
Kit-1856 | PRMT3 Homogeneous Assay Kit | +Inquiry |
Kit-1855 | PRMT3 Chemiluminescent Assay Kit | +Inquiry |
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