Recombinant Human BID, GST-tagged
Cat.No. : | BID-6977H |
Product Overview : | Recombinant full-length human BID was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | BID is a BH3 interacting death domain that heterodimerizes with either agonist BAX or antagonist BCL2. BID is a member of the BCL-2 family of cell death regulators and is a mediator of mitochondrial damage induced by caspase-8 (CASP8). BID initiates apoptosis by binding to regulatory sites on prosurvival BCL2 proteins to directly neutralize their function. Multiple alternatively spliced transcript variants of BID have been found, but the full-length nature of some variants has not been defined. BID together with Cathepsins play an important role in the actions of Camptothecin on breast cancer cells. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~52kDa |
Protein length : | Full length |
Purity : | >85% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.2 μg/μl |
Gene Name : | BID BH3 interacting domain death agonist [ Homo sapiens ] |
Official Symbol : | BID |
Synonyms : | BID; BH3 interacting domain death agonist; BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence; FP497; MGC15319; MGC42355; |
Gene ID : | 637 |
mRNA Refseq : | NM_001196 |
Protein Refseq : | NP_001187 |
MIM : | 601997 |
UniProt ID : | P55957 |
Chromosome Location : | 22q11.2 |
Pathway : | Activation and oligomerization of BAK protein, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Activation, translocation and oligomerization of BAX, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; |
Function : | death receptor binding; protein binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
BID-1032M | Recombinant Mouse BID Protein, His (Fc)-Avi-tagged | +Inquiry |
Bid-711M | Recombinant Mouse Bid Protein, MYC/DDK-tagged | +Inquiry |
BID-2006H | Recombinant Human BID Protein, His-tagged | +Inquiry |
Bid-4029M | Active Recombinant Mouse Bid protein(Met1-Asp195), His&GST-tagged | +Inquiry |
BID-3838H | Active Recombinant Human BID protein | +Inquiry |
◆ Lysates | ||
BID-8456HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
BID-8455HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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