Recombinant Human KDM5C, GST-tagged
Cat.No. : | KDM5C-7032H |
Product Overview : | Recombinant human KDM5C (1-671) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | KDM5C or lysine (K)-specific demethylase 5C is a member of the SMCY homolog family that encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers.KDM5C is mainly expressed in brain and skeletal muscle. KDM5C is involved in the regulation of transcription and chromatin remodelling that cause X-linked mental retardation. KDM5C is also essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~118 kDa |
Protein length : | 1-671 aa |
Purity : | >80% |
Applications : | Western Blot |
Storage : | Store at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | KDM5C lysine (K)-specific demethylase 5C [ Homo sapiens ] |
Official Symbol : | KDM5C |
Synonyms : | KDM5C; lysine (K)-specific demethylase 5C; JARID1C, jumonji, AT rich interactive domain 1C , Jumonji, AT rich interactive domain 1C (RBP2 like) , SMCX, Smcy homolog, X linked (mouse); lysine-specific demethylase 5C; DXS1272E; XE169; protein SmcX; selected cDNA on X; Smcy homolog, X-linked; Smcx homolog, X chromosome; histone demethylase JARID1C; JmjC domain-containing protein SMCX; Jumonji/ARID domain-containing protein 1C; Jumonji, AT rich interactive domain 1C (RBP2-like); MRXJ; SMCX; MRXSJ; MRXSCJ; JARID1C; |
Gene ID : | 8242 |
mRNA Refseq : | NM_001146702 |
Protein Refseq : | NP_001140174 |
MIM : | 314690 |
UniProt ID : | P41229 |
Chromosome Location : | Xp11.22-p11.21 |
Function : | DNA binding; histone demethylase activity (H3-K4 specific); metal ion binding; molecular_function; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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