Recombinant Human ELK1, GST-tagged
Cat.No. : | KCNH8-7049H |
Product Overview : | Recombinant full-length human ELK1 was expressed in E. coli cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | ELK1 is a member of the ETS oncogene family of transcription factors. ELK1 protein interacts with promoter of the c-fos proto-oncogene and has been shown to be involved in the Ras-Raf-MAPK signaling cascade. Immature phosphorylation of transcription factor ELK-1 is implicated in premature aging syndrome and insulin resistance. Expression studies have revealed that elevated expression of ELK1-like protein in human esophageal can result in squamous cell carcinoma. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~81 kDa |
Protein length : | Full length |
Purity : | >75% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.2 μg/μl |
Storage Buffer : | Sterile distilled water at a concentration of 1mg/ml or less. |
Gene Name : | KCNH8 potassium voltage-gated channel, subfamily H (eag-related), member 8 [ Homo sapiens ] |
Official Symbol : | KCNH8 |
Synonyms : | KCNH8; potassium voltage-gated channel, subfamily H (eag-related), member 8; potassium voltage-gated channel subfamily H member 8; elk3; Kv12.1; hElk1; ELK channel 3; ether-a-go-go-like potassium channel 1; ether-a-go-go-like potassium channel 3; voltage-gated potassium channel subunit Kv12.1; ELK; ELK1; |
Gene ID : | 131096 |
mRNA Refseq : | NM_144633 |
Protein Refseq : | NP_653234 |
MIM : | 608260 |
UniProt ID : | Q96L42 |
Chromosome Location : | 3p24.3 |
Pathway : | Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem; |
Function : | sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; two-component sensor activity; voltage-gated ion channel activity; voltage-gated potassium channel activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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