Recombinant Human AMN, His-tagged

• Cat.No.: AMN-7084H
• Product Overview: Recombinant human AMN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Specification

• Description: AMN, also known as amnionless, is a type I transmembrane protein. A complex of amnionless and cubilin forms the cubam receptor. This protein is necessary for efficient absorption of vitamin B12. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,10% glycerol,1mM DTT
• Molecular Mass: 38.2 kDa (361aa)
• Protein length: 20-357aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVSKLWVP NTDFDVAANW SQNRTPCAGG AVEFPADKMV SVLVQEGHAV SDMLLPLDGE LVLASGAGFG VSDVGSHLDC GAGEPAVFRD SDRFSWHDPH LWRSGDEAPG LFFVDAERVP CRHDDVFFPP SASFRVGLGP GASPVRVRSI SALGRTFTRD EDLAVFLASR AGRLRFHGPG ALSVGPEDCA DPSGCVCGNA EAQPWICAAL LQPLGGRCPQ AACHSALRPQ GQCCDLCGAV VLLTHGPAFD LERYRARILD TFLGLPQYHG LQVAVSKVPR SSRLREADTE IQVVLVENGP ETGGAGRLAR ALLADVAENG EALGVLEATM RESGAHVWGS S
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: AMN amnionless homolog (mouse) [ Homo sapiens ]
• Official Symbol: AMN
• Synonyms: AMN; amnionless homolog (mouse); protein amnionless; visceral endoderm-specific type 1 transmembrane protein; PRO1028
• Gene ID: 81693
• mRNA Refseq: NM_030943
• Protein Refseq: NP_112205
• MIM: 605799
• UniProt ID: Q9BXJ7
• Chromosome Location: 14q32.32
• Pathway: HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem