Recombinant Human XRCC3, His-tagged

• Cat.No.: XRCC3-7094H
• Product Overview: Recombinant human XRCC3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: XRCC3, also known as RAD51-like, belongs to the RecA family and RAD51 subfamily. It participates in homologous recombination to maintain chromosome stability and repair DNA damage. This protein functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 40.0 kDa (366aa)
• Protein length: 1-346aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MDLDLLDLNP RIIAAIKKAK LKSVKEVLHF SGPDLKRLTN LSSPEVWHLL RTASLHLRGS SILTALQLHQQKERFPTQHQ RLSLGCPVLD ALLRGGLPLD GITELAGRSS AGKTQLALQL CLAVQFPRQH GGLEAGAVYI CTEDAFPHKR LQQLMAQQPRLRTDVPGELL QKLRFGSQIF IEHVADVDTL LECVNKKVPV LLSRGMARLV VIDSVAAPFR CEFDSQASAP RARHLQSLGA TLRELSSAFQSPVLCINQVT EAMEEQGAAH GPLGFWDERV SPALGITWAN QLLVRLLADR LREEEAALGC PARTLRVLSA PHLPPSSCSY TISAEGVRGTPGTQSH
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [ Homo sapiens ]
• Official Symbol: XRCC3
• Synonyms: XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; DNA repair protein XRCC3; RAD51 like; X-ray repair cross-complementing protein 3; CMM6
• Gene ID: 7517
• mRNA Refseq: NM_001100118
• Protein Refseq: NP_001093588
• MIM: 600675
• UniProt ID: O43542
• Chromosome Location: 14q32.3
• Pathway: Fluoropyrimidine Activity, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem
• Function: ATP binding; DNA binding; DNA-dependent ATPase activity; nucleotide binding; protein binding