"TBPL1" Related Products

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Recombinant Human TBPL1, His-tagged

Cat.No.: TBPL1-7114H
Product Overview: Recombinant human TBPL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: TBPL1, also known as STUD, TLF, TLP and TRF2, belongs to the TBP family. The TATA box-binding protein (TBP) is an essential component of the basal transcriptional machinery. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 1mM EDTA
Molecular Mass: 23.3kDa (209aa)
Protein length: 1-186aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDADSDV ALDILITNVV CVFRTRCHLN LRKIALEGAN VIYKRDVGKV LMKLRKPRIT ATIWSSGKII CTGATSEEEA KFGARRLARS LQKLGFQVIF TDFKVVNVLA VCNMPFEIRL PEFTKNNRPH ASYEPELHPA VCYRIKSLRA TLQIFSTGSI TVTGPNVKAV ATAVEQIYPF VFESRKEIL
Purity: >90 % by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml
Gene Name: TBPL1 TBP-like 1 [ Homo sapiens ]
Official Symbol: TBPL1
Synonyms: TBPL1; TBP-like 1; TATA box-binding protein-like protein 1; STUD; TLF; TLP; TRF2; TBP-related protein; TBP-related factor 2; 21-kDA TBP-like protein; second TBP of unique DNA protein; TATA box-binding protein-related factor 2; MGC:8389; MGC:9620;
Gene ID: 9519
mRNA Refseq: NM_001253676
Protein Refseq: NP_001240605
MIM: 605521
UniProt ID: P62380
Chromosome Location: 6q22.1-q22.3
Pathway: Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Herpes simplex infection, organism-specific biosystem;
Function: DNA binding; binding; transcription coactivator activity;

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