"SDHAF2" Related Products

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Recombinant Human SDHAF2, His-tagged

Cat.No.: SDHAF2-7119H
Product Overview: Recombinant human SDHAF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: SDHAF2 is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Defects in SDHAF2 are the cause of hereditary paragangliomas type 2 (PGL2), also known as familial non-chromaffin paragangliomas type 2. Paragangliomas refer to rare and mostly benign tumors that arise from any component of the neuroendocrine system.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
Molecular Mass: 19.0kDa (160aa)
Protein length: 30-166aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQHMTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml
Gene Name: SDHAF2 succinate dehydrogenase complex assembly factor 2 [ Homo sapiens ]
Official Symbol: SDHAF2
Synonyms: SDHAF2; succinate dehydrogenase complex assembly factor 2; C11orf79, chromosome 11 open reading frame 79 , paraganglioma or familial glomus tumors 2 , PGL2; succinate dehydrogenase assembly factor 2, mitochondrial; FLJ20487; SDH5; hSDH5; SDH assembly factor 2; succinate dehydrogenase subunit 5, mitochondrial; PGL2; C11orf79;
Gene ID: 54949
mRNA Refseq: NM_017841
Protein Refseq: NP_060311
MIM: 613019
UniProt ID: Q9NX18
Chromosome Location: 11q12.2
Function: protein binding;

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