Recombinant Human SDHAF2, His-tagged

• Cat.No.: SDHAF2-7119H
• Product Overview: Recombinant human SDHAF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: SDHAF2 is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Defects in SDHAF2 are the cause of hereditary paragangliomas type 2 (PGL2), also known as familial non-chromaffin paragangliomas type 2. Paragangliomas refer to rare and mostly benign tumors that arise from any component of the neuroendocrine system.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
• Molecular Mass: 19.0kDa (160aa)
• Protein length: 30-166aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQHMTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: SDHAF2 succinate dehydrogenase complex assembly factor 2 [ Homo sapiens ]
• Official Symbol: SDHAF2
• Synonyms: SDHAF2; succinate dehydrogenase complex assembly factor 2; C11orf79, chromosome 11 open reading frame 79 , paraganglioma or familial glomus tumors 2 , PGL2; succinate dehydrogenase assembly factor 2, mitochondrial; FLJ20487; SDH5; hSDH5; SDH assembly factor 2; succinate dehydrogenase subunit 5, mitochondrial; PGL2; C11orf79
• Gene ID: 54949
• mRNA Refseq: NM_017841
• Protein Refseq: NP_060311
• MIM: 613019
• UniProt ID: Q9NX18
• Chromosome Location: 11q12.2
• Function: protein binding