Rabbit Anti-Human DUOX2 Polyclonal Antibody


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Rabbit Anti-Human DUOX2 Polyclonal Antibody

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Cat. No. : CPBT-32950RH
ProductOverview : Rabbit polyclonal to human DUOX2.
Antigen Description : The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Immunogen : Synthetic peptide corresponding to internal sequence amino acids of Human DUOX2.
Host animal : Rabbit
Cross reactivity : Reacts with Rat, Human; Predicted to work withMouse
Isotype : IgG
Purity : Immunogen affinity purified
Applications : WB, IHC-P
Positive control : HeLa, Jurkat, MCF7 and SMMC cell lysates.
Sequencesimilarities : In the N-terminal section; belongs to the peroxidase family.Contains 3 EF-hand domains.Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.
Concentration : 100 µg at 0.5mg/ml
Form : Liquid
Storage Buffer : Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azideConstituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
nullValue_other :
FunctionNAD(P)H oxidase activity; calcium ion binding; heme binding; peroxidase activity
Gene Name : DUOX2 dual oxidase 2 [ Homo sapiens ]
Official Symbol : DUOX2
Synonyms : DUOX2; dual oxidase 2; TDH6; LNOX2; THOX2; NOXEF2; P138-TOX; dual oxidase 2; long NOX 2; large NOX 2; thyroid oxidase 2; p138 thyroid oxidase; NADPH thyroid oxidase 2; flavoprotein NADPH oxidase; dual oxidase-like domains 2; NADPH oxidase/peroxidase DUOX2; NADH/NADPH thyroid oxidase p138-tox; nicotinamide adenine dinucleotide phosphate oxidase; EC; EC 1.11.1
Gene ID : 50506
mRNA Refseq : NM_014080
Protein Refseq : NP_054799
MIM : 606759
UniProt ID : Q9NRD8
Chromosome Location : 15q15.3
Pathway : NOD pathway, organism-specific biosystem
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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