Rabbit Anti-Human DUOX2 Polyclonal Antibody CPBT-32950RH

Rabbit Anti-Human DUOX2 Polyclonal Antibody

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Rabbit Anti-Human DUOX2 Polyclonal Antibody

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Cat. No. : CPBT-32950RH
ProductOverview : Rabbit polyclonal to human DUOX2.
Antigen Description : The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Immunogen : Synthetic peptide corresponding to internal sequence amino acids of Human DUOX2.
Host animal : Rabbit
Cross reactivity : Reacts with Rat, Human; Predicted to work withMouse
Isotype : IgG
Purity : Immunogen affinity purified
Applications : WB, IHC-P
Positive control : HeLa, Jurkat, MCF7 and SMMC cell lysates.
Sequencesimilarities : In the N-terminal section; belongs to the peroxidase family.Contains 3 EF-hand domains.Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.
Concentration : 100 µg at 0.5mg/ml
Form : Liquid
Storage Buffer : Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azideConstituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
nullValue_other :
FunctionNAD(P)H oxidase activity; calcium ion binding; heme binding; peroxidase activity
Gene Name : DUOX2 dual oxidase 2 [ Homo sapiens ]
Official Symbol : DUOX2
Synonyms : DUOX2; dual oxidase 2; TDH6; LNOX2; THOX2; NOXEF2; P138-TOX; dual oxidase 2; long NOX 2; large NOX 2; thyroid oxidase 2; p138 thyroid oxidase; NADPH thyroid oxidase 2; flavoprotein NADPH oxidase; dual oxidase-like domains 2; NADPH oxidase/peroxidase DUOX2; NADH/NADPH thyroid oxidase p138-tox; nicotinamide adenine dinucleotide phosphate oxidase; EC 1.6.3.1; EC 1.11.1
Gene ID : 50506
mRNA Refseq : NM_014080
Protein Refseq : NP_054799
MIM : 606759
UniProt ID : Q9NRD8
Chromosome Location : 15q15.3
Pathway : NOD pathway, organism-specific biosystem

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