Recombinant Human STAMBPL1, His-tagged

• Cat.No.: STAMBPL1-7255H

Specification

• product overview: Recombinant human STAMBPL1 protein, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques.
• description: STAMBPL1 is a zinc metalloprotease that specifically cleaves "Lys-63"-linked polyubiquitin chains, but doesn't cleave "Lys-48"-linked polyubiquitin chains. The JAMM motif is essential for the protease activity.
• source: E. coli
• species: Human
• tag: His
• form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol.
• molecular mass: 52 kDa (458aa)
• protein length: 1-436aa
• aa sequence: MGSSHHHHHH SSGLVPRGSQ SHMDQPFTVN SLKKLAAMPD HTDVSLSPEE RVRALSKLGC NITISEDITP RRYFRSGVEM ERMASVYLEEGNLENAFVLY NKFITLFVEK LPNHRDYQQC AVPEKQDIMK KLKEIAFPRT DELKNDLLKK YNVEYQEYLQ SKNKYKAEIL KKLEHQRLIE AERKRIAQMR QQQLESEQFL FFEDQLKKQE LARGQMRSQQ TSGLSEQIDG SALSCFSTHQ NNSLLNVFAD QPNKSDATNY ASHSPPVNRALTPAATLSAV QNLVVEGLRC VVLPEDLCHK FLQLAESNTV RGIETCGILC GKLTHNEFTI THVIVPKQSA GPDYCDMENV EELFNVQDQH DLLTLGWIHT HPTQTAFLSS VDLHTHCSYQ LMLPEAIAIV CSPKHKDTGI FRLTNAGMLE VSACKKKGFH PHTKEPRLFS ICKHVLVKDIKIIVLDLR
• purity: >90% by SDS - PAGE
• applications: SDS-PAGE
• storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• concentration: 0.5 mg/ml

Gene Information

• gene name: STAMBPL1 STAM binding protein-like 1 [ Homo sapiens ]
• official symbol: STAMBPL1
• synonyms: STAMBPL1; STAM binding protein-like 1; AMSH-like protease; ALMalpha; AMSH FP; AMSH LP; associated molecule with the SH3 domain of STAM (AMSH) Family Protein; associated molecule with the SH3 domain of STAM (AMSH) like protein; bA399O19.2; FLJ31524; KIAA1373; associated molecule with the SH3 domain of STAM (AMSH) - Family Protein; AMSH-FP; AMSH-LP
• Gene ID: 57559
• mrna refseq: NM_020799
• protein refseq: NP_065850
• mim: 612352
• uniprot id: Q96FJ0
• chromosome location: 10q23.32
• pathway: TGF-beta Receptor Signaling Pathway, organism-specific biosystem
• function: metal ion binding; metallopeptidase activity; peptidase activity; protein binding