Recombinant Human CRYBA4, His-tagged

• Cat.No.: CRYBA4-3607H
• Product Overview: Recombinant human CRYBA4 protein, fused to His-tag at N-terminus, was expressed in E.coliand purified by using conventional chromatography.

Specification

• Cat. No.: CRYBA4-3607H
• Description: CRYBA4, also known as Beta-crystallin A4, belongs to the beta/gamma-crystallinfamily that are the dominant structural components of the vertebrate eye lens. Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
• Molecular Weight: 24.5 kDa(216aa), confirmed by MALDI-TOF
• Purity: >95% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MTLQCTKSAG PWKMVVWDED GFQGRRHEFT AECPSVLELG FETVRSLKVL SGAWVGFEHA GFQGQQYILERGEYPSWDAW GGNTAYPAER LTSFRPAACA NHRDSRLTIF EQENFLGKKG ELSDDYPSLQ AMGWEGNEVG SFHVHSGAWV CSQFPGYRGFQYVLECDHHS GDYKHFREWG SHAPTFQVQS IRRIQQ
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CRYBA4 crystallin, beta A4 [ Homo sapiens ]
• Official Symbol: CRYBA4
• Synonyms: CRYBA4; MCOPCT4;crystallin, beta A4; beta-crystallin A4;OTTHUMP00000198864;beta-A4 crystallin;eye lens structural protein;crystallin, beta polypeptide A4
• Gene ID: 1413
• mRNA Refseq: NM_001886
• Protein Refseq: NP_001877
• MIM: 123631
• UniProt ID: P53673
• Chromosome Location: 22q11.2-q13.1; 22q12.1
• Function: molecular_function; structural constituent of eye lens