"CHMP2B" Related Products

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Recombinant Human CHMP2B, His-tagged

Cat. No.: CHMP2B-3578H
Product Overview: Recombinant human CHMP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-213 aa).
Description: CHMP2B belongs to the vacuolar sorting protein family. It is a component of the ESCRT-III complex. This complex is crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
Molecular Weight: 26.1 kDa (233aa), confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher)
Purity: > 90 % by SDS - PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASLFKKKTV DDVIKEQNRE LRGTQRAIIR DRAALEKQEK QLELEIKKMA KIGNKEACKV LAKQLVHLRK QKTRTFAVSS KVTSMSTQTK VMNSQMKMAG AMSTTAKTMQ AVNKKMDPQK TLQTMQNFQK ENMKMEMTEE MINDTLDDIF DGSDDEEESQ DIVNQVLDEI GIEISGKMAK APSAARSLPS ASTSKATISD EEIERQLKAL GVD
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CHMP2B chromatin modifying protein 2B [ Homo sapiens ]
Official Symbol: CHMP2B
Synonyms: CHMP2B; DMT1; VPS2B; VPS2-2; CHMP2.5; CGI-84; DKFZp564O123; chromatin modifying protein 2B ; charged multivesicular body protein 2b; hVps2-2; VPS2 homolog B; chromatin-modifying protein 2b; vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B (S. cerevisiae); Charged multivesicular body protein 2b; Vacuolar protein sorting-associated protein 2-2; OTTHUMP00000213795;OTTHUMP00000213812; OTTHUMP00000213813; Chromatin-modifying protein 2b
Gene ID: 25978
mRNA Refseq: NM_014043
Protein Refseq: NP_054762
MIM: 609512
UniProt ID: Q9UQN3
Chromosome Location: 3p11.2
Function: protein binding; protein binding

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