Recombinant Human RAB3A, His-tagged

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Recombinant Human RAB3A, His-tagged

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Cat. No. : RAB3A-3586H
Product Overview : Recombinant human RAB3A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-220aa).
Description : Rab3A belongs to the small GTPase superfamily, Rab family. It is a small, Ras-like GTPase expressed in neuroendocrine cells, in which it is associated with secretory vesicle membranes and regulates exocytosis. This protein could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Molecular Weight : 27.1 kDa (240aa), confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MASATDSRYG QKESSDQNFD YMFKILIIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTIYRNDKR IKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NAVQDWSTQI KTYSWDNAQV LLVGNKCDME DERVVSSERG RQLADHLGFE FFEASAKDNI NVKQTFERLV DVICEKMSES LDTADPAVTG AKQGPQLSDQ QVPPHQDCAC
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDBrendering based on 1zbd. :

Gene Name : RAB3A RAB3A, member RAS oncogene family [ Homo sapiens ]
Official Symbol : RAB3A
Synonyms : RAB3A;RAB3A, member RAS oncogene family; ras-related protein Rab-3A; OTTHUMP00000174429; RAS-associated protein RAB3A; Ras-related protein Rab-3A
Gene ID : 5864
mRNA Refseq : NM_002866
Protein Refseq : NP_002857
MIM : 179490
UniProt ID : P20336
Chromosome Location : 19p13.2
Function : ATPase activator activity; ATPase binding; GTP binding; GTPase activity; GTPase binding; nucleotide binding; protein C-terminus binding; protein binding

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