"NT5C3" Related Products

Recombinant Human NT5C3 protein

Cat.No.: NT5C3-7371H
Product Overview: Recombinant Human NT5C3(Met 12-Leu 297) was expressed in E. coli.
Description: This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.
Source: E. coli
Species: Human
Predicted N Terminal: Met 12
Form: Lyophilized from sterile PBS
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Molecular Mass: The recombinant human NT5C3 consists of 286 amino acids and predicts a molecular mass of 32.7KDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions.
Protein length: Met 12-Leu 297
Purity: > 92 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade
Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Reconstitute in PBS or others.
Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name: NT5C3 5-nucleotidase, cytosolic III [ Homo sapiens ]
Official Symbol: NT5C3
Synonyms: NT5C3; 5-nucleotidase, cytosolic III; cytosolic 5-nucleotidase 3; cN III; P5N 1; PN I; PSN1; UMPH; UMPH1; pyrimidine 5-nucleotidase 1; uridine 5-monophosphate hydrolase 1; p36; PN-I; P5N-1; cN-III; MGC27337; MGC87109; MGC87828;
Gene ID: 51251
mRNA Refseq: NM_001002010
Protein Refseq: NP_001002010
MIM: 606224
UniProt ID: Q9H0P0
Chromosome Location: 7p14.3
Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function: 2-phosphotransferase activity; 2-phosphotransferase activity; 5-nucleotidase activity; 5-nucleotidase activity; 5-nucleotidase activity; hydrolase activity; magnesium ion binding; nucleotide binding;

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