Recombinant Human NUDT14, His-tagged

• Cat.No.: NUDT14-7521H
• Product Overview: Recombinant human NUDT14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: Uridine diphosphate glucose pyrophosphatase, also known as NUDT14, is a 222 amino acid cytoplasmic protein that contains one nudix hydrolase domain and belongs to the nudix hydrolase family. NUDT14 hydrolyzes ADP-ribose into ribose 5-phosphate and AMP, and UDP-glucose to glucose 1-phosphate and UMP. Existing as a homodimer, NUDT14 binds magnesium as a cofactor and is encoded by a gene located on human chromosome 14.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 26.5 kDa (245aa) confirmed by MALDI-TOF
• Protein length: 1-222aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMERIEGA SVGRCAASPY LRPLTLHYRQ NGAQKSWDFM KTHDSVTVLL FNSSRRSLVL VKQFRPAVYA GEVERRFPGS LAAVDQDGPR ELQPALPGSA GVTVELCAGL VDQPGLSLEE VACKEAWEEC GYHLAPSDLR RVATYWSGVG LTGSRQTMFY TEVTDAQRSG PGGGLVEEGE LIEVVHLPLE GAQAFADDPD IPKTLGVIFG VSWFLSQVAP NLDLQ
• Purity: >95% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: NUDT14?nudix (nucleoside diphosphate linked moiety X)-type motif 14 [?Homo sapiens?]
• Official Symbol: NUDT14
• Synonyms: NUDT14; UGPP; UGPPase; uridine diphosphate glucose pyrophosphatase; UDPG pyrophosphatase; UDP-sugar diphosphatase; nudix (nucleoside diphosphate linked moiety X)-type motif 14; nucleoside diphosphate linked moiety X-type motif 14; Nucleoside diphosphate-linked moiety X motif 14; Nudix motif 14; EC 3.6.1.45
• Gene ID: 256281
• mRNA Refseq: NM_177533
• Protein Refseq: NP_803877
• MIM: 609219
• UniProt ID: O95848
• Chromosome Location: 14q32.33
• Function: UDP-sugar diphosphatase activity; metal ion binding; protein binding