"RAP2B" Related Products

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Recombinant Human RAP2B, His-tagged

Cat.No.: RAP2B-7522H
Product Overview: Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Antigen Description: Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Molecular Mass: 22.9kDa (206aa) confirmed by MALDI-TOF
Protein length: 1-183aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMREYKVV VLGSGGVGKS ALTVQFVTGS FIEKYDPTIE DFYRKEIEVD SSPSVLEILD TAGTEQFASM RDLYIKNGQG FILVYSLVNQ QSFQDIKPMR DQIIRVKRYE RVPMILVGNK VDLEGEREVS YGEGKALAEE WSCPFMETSA KNKASVDELF AEIVRQMNYA AQPNGDEGCC SACVIL
Purity: >95% as determined by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml
Gene Name: RAP2B RAP2B, member of RAS oncogene family [ Homo sapiens ]
Official Symbol: RAP2B
Synonyms: RAP2B; RAP2B, member of RAS oncogene family; ras-related protein Rap-2b; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; small GTP binding protein; MGC20484;
Gene ID: 5912
mRNA Refseq: NM_002886
Protein Refseq: NP_002877
MIM: 179541
UniProt ID: P61225
Chromosome Location: 3q25.2
Function: GTP binding; GTPase activity; nucleotide binding; protein domain specific binding;

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